3ky7: Difference between revisions
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New page: '''Unreleased structure''' The entry 3ky7 is ON HOLD Authors: Halavaty, A.S., Minasov, G., Winsor, J., Dubrovska, I., Shuvalova, L., See, R., Zoraghi, R., Reiner, N., Anderson, W.F., Ce... |
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==2.35 Angstrom resolution crystal structure of a putative tRNA (guanine-7-)-methyltransferase (trmD) from Staphylococcus aureus subsp. aureus MRSA252== | |||
<StructureSection load='3ky7' size='340' side='right' caption='[[3ky7]], [[Resolution|resolution]] 2.35Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3ky7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staar Staar]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KY7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KY7 FirstGlance]. <br> | |||
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SAR1216, trmD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=282458 STAAR])</td></tr> | |||
'' | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.221 and 2.1.1.228 2.1.1.221 and 2.1.1.228] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ky7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ky7 OCA], [http://pdbe.org/3ky7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ky7 RCSB], [http://www.ebi.ac.uk/pdbsum/3ky7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ky7 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/TRMD_STAAR TRMD_STAAR]] Specifically methylates guanosine-37 in various tRNAs (By similarity). | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ky/3ky7_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ky7 ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Staar]] | |||
[[Category: Transferase]] | |||
[[Category: Anderson, W F]] | |||
[[Category: Structural genomic]] | |||
[[Category: Dubrovska, I]] | |||
[[Category: Halavaty, A S]] | |||
[[Category: Minasov, G]] | |||
[[Category: Reiner, N]] | |||
[[Category: See, R]] | |||
[[Category: Shuvalova, L]] | |||
[[Category: Winsor, J]] | |||
[[Category: Zoraghi, R]] | |||
[[Category: Csgid]] | |||
[[Category: Infectious disease]] | |||
[[Category: Methyltransferase]] | |||
[[Category: S-adenosyl-l-methionine]] | |||
[[Category: Trna processing]] | |||
Latest revision as of 11:44, 1 November 2017
2.35 Angstrom resolution crystal structure of a putative tRNA (guanine-7-)-methyltransferase (trmD) from Staphylococcus aureus subsp. aureus MRSA2522.35 Angstrom resolution crystal structure of a putative tRNA (guanine-7-)-methyltransferase (trmD) from Staphylococcus aureus subsp. aureus MRSA252
Structural highlights
Function[TRMD_STAAR] Specifically methylates guanosine-37 in various tRNAs (By similarity). Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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