Sandbox21: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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-==This is a placeholder==
+'''This sandbox is in use until June 1, 2009 for UMass Chemistry 490a. Others please do not edit this page. Thanks!
-This is a placeholder text to help you get started in
-placing a Jmol applet on your page. At any time, click
-"Show Preview" at the bottom of this page to see how it goes.
-Replace the PDB id (use lowercase!) after the STRUCTURE_ and after PDB= to load
+Chem 490A: Proteopedia Assignment
-and display another structure.
-{{STRUCTURE_3cin |  PDB=3cin  |  SCENE=  }}
+by Kevin Chen 3-3-09
+==Trypsin==
+Trypsin is an enzyme that breaks down protein, that is produced in the pancreas and then secreted in to the small intestines. It is a homolog of chymotrypsin and it works by cleaving at the peptide bond after residues with long, positively charged side chains. An aspartate residue which attracts and stabilizes a positively charged arginine or lysine residue in the substrate. The disease of cystic fibrosis is the result of deficiency in transport of trypsin and other digestive enzymes from the pancreas.
+==Structure==
+This is the protein Trypsin,it has <scene name='Sandbox21/Trypsin_alpha_helix/1'>alpha helices</scene> (shown in red) and also <scene name='Sandbox21/Trypsin_beta_sheets/1'>beta sheets</scene> (shown in blue), also the <scene name='Sandbox21/Trypsin_hydrophobic/1'>amphipathic</scene> parts of Trypsin are found throught out the molecule. Image of the crystal complex between bovine trypsin and Veronica Hederfolia trypsin found at [[2cmy]].
-<applet load='1crf' size='300' frame='true' align='right' caption='Insert caption here' />
+{{STRUCTURE_2cmy |  PDB=2cmy  |  SCENE=  }}
-This is the protein
+Reference-
+Berg, Tymoczko, Stryer, Biochemistry 6th ed. W.H. Freeman and CO.