8s31: Difference between revisions

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'''Unreleased structure'''


The entry 8s31 is ON HOLD  until Paper Publication
==Crystal structure of human PLK1 Polo-Box Domain in complex with Mis18BP1==
 
<StructureSection load='8s31' size='340' side='right'caption='[[8s31]], [[Resolution|resolution]] 2.13&Aring;' scene=''>
Authors: Jeyaprakash, A.A., Medina-Pritchard, B.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8s31]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8S31 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8S31 FirstGlance]. <br>
Description: Crystal structure of human PLK1 Polo-Box Domain in complex with Mis18BP1
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.134&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8s31 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8s31 OCA], [https://pdbe.org/8s31 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8s31 RCSB], [https://www.ebi.ac.uk/pdbsum/8s31 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8s31 ProSAT]</span></td></tr>
[[Category: Medina-Pritchard, B]]
</table>
[[Category: Jeyaprakash, A.A]]
== Function ==
[https://www.uniprot.org/uniprot/M18BP_HUMAN M18BP_HUMAN] Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.<ref>PMID:17199038</ref> <ref>PMID:17339379</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Jeyaprakash AA]]
[[Category: Medina-Pritchard B]]

Latest revision as of 16:06, 21 August 2024

Crystal structure of human PLK1 Polo-Box Domain in complex with Mis18BP1Crystal structure of human PLK1 Polo-Box Domain in complex with Mis18BP1

Structural highlights

8s31 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.134Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

M18BP_HUMAN Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.[1] [2]

References

  1. ↑ Fujita Y, Hayashi T, Kiyomitsu T, Toyoda Y, Kokubu A, Obuse C, Yanagida M. Priming of centromere for CENP-A recruitment by human hMis18alpha, hMis18beta, and M18BP1. Dev Cell. 2007 Jan;12(1):17-30. doi: 10.1016/j.devcel.2006.11.002. PMID:17199038 doi:http://dx.doi.org/10.1016/j.devcel.2006.11.002
  2. ↑ Maddox PS, Hyndman F, Monen J, Oegema K, Desai A. Functional genomics identifies a Myb domain-containing protein family required for assembly of CENP-A chromatin. J Cell Biol. 2007 Mar 12;176(6):757-63. PMID:17339379 doi:10.1083/jcb.200701065

8s31, resolution 2.13Å

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