8xwf: Difference between revisions
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==Structure of CXCR2 bound to CXCL3 (Ligand-receptor focused map)== | |||
<StructureSection load='8xwf' size='340' side='right'caption='[[8xwf]], [[Resolution|resolution]] 3.65Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8xwf]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8XWF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8XWF FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.65Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8xwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8xwf OCA], [https://pdbe.org/8xwf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8xwf RCSB], [https://www.ebi.ac.uk/pdbsum/8xwf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8xwf ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CXCL3_HUMAN CXCL3_HUMAN] Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.<ref>PMID:10095777</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Banerjee R]] | |||
[[Category: Ganguly M]] | |||
[[Category: Nureki O]] | |||
[[Category: Saha S]] | |||
[[Category: Sano FK]] | |||
[[Category: Sharma S]] | |||
[[Category: Shihoya W]] | |||
[[Category: Shukla AK]] |