8x0g: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-'''Unreleased structure'''
-The entry 8x0g is ON HOLD
+==Human FL Metabotropic glutamate receptor 5, mGlu5-5M with quisqualate, Acc conformation (purified with PAM VU0409551 but not modelled)==
+<StructureSection load='8x0g' size='340' side='right'caption='[[8x0g]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-Authors: Vinothkumar, K.R., Lebon, G., Cannone, G.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8x0g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8X0G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8X0G FirstGlance]. <br>
-Description: Human FL Metabotropic glutamate receptor 5, mGlu5-5M with quisqualate and PAM
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=QUS:(S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC+ACID'>QUS</scene></td></tr>
-[[Category: Cannone, G]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8x0g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8x0g OCA], [https://pdbe.org/8x0g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8x0g RCSB], [https://www.ebi.ac.uk/pdbsum/8x0g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8x0g ProSAT]</span></td></tr>
-[[Category: Vinothkumar, K.R]]
+</table>
-[[Category: Lebon, G]]
+== Function ==
+[https://www.uniprot.org/uniprot/GRM5_HUMAN GRM5_HUMAN] Receptor for glutamate. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current.
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Cannone G]]
+[[Category: Lebon G]]
+[[Category: Vinothkumar KR]]