8qbe: Difference between revisions
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==Compact state - Pil1 in native eisosome lattice bound to plasma membrane microdomain== | |||
<StructureSection load='8qbe' size='340' side='right'caption='[[8qbe]], [[Resolution|resolution]] 3.67Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8qbe]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QBE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QBE FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.67Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qbe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qbe OCA], [https://pdbe.org/8qbe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qbe RCSB], [https://www.ebi.ac.uk/pdbsum/8qbe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qbe ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/PIL1_YEAST PIL1_YEAST] Negative regulator of cell wall integrity (CWI) in unstressed cells, probably by inhibiting protein kinase PKH1/PHK2 activity and regulating their downstream CWI pathways PKC1-MAP kinase pathway and protein kinase YPK1 pathway. Activity may be regulated by the transient increase of sphingolipid long chain bases (LCBs) during heat stress.<ref>PMID:15016821</ref> | ||
[[Category: | == References == | ||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae]] | |||
[[Category: Desfosses A]] | |||
[[Category: Kefauver JM]] | |||
[[Category: Loewith RJ]] | |||
[[Category: Zou L]] |