8k11: Difference between revisions

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-'''Unreleased structure'''
-The entry 8k11 is ON HOLD
+==SID1 transmembrane family member 2==
+<StructureSection load='8k11' size='340' side='right'caption='[[8k11]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
-Authors: Guo, H., Qi, C., Lu, Y., Yang, H., Zhu, Y., Sun, F., Ji, X.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8k11]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8K11 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8K11 FirstGlance]. <br>
-Description: To be published
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-[[Category: Lu, Y]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8k11 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8k11 OCA], [https://pdbe.org/8k11 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8k11 RCSB], [https://www.ebi.ac.uk/pdbsum/8k11 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8k11 ProSAT]</span></td></tr>
-[[Category: Zhu, Y]]
+</table>
-[[Category: Guo, H]]
+== Function ==
-[[Category: Yang, H]]
+[https://www.uniprot.org/uniprot/SIDT2_HUMAN SIDT2_HUMAN] Mediates the translocation of RNA and DNA across the lysosomal membrane during RNA and DNA autophagy (RDA), a process in which RNA or DNA is directly imported into lysosomes in an ATP-dependent manner, and degraded (PubMed:27046251, PubMed:27846365). Involved in the uptake of single-stranded oligonucleotides by living cells, a process called gymnosis (PubMed:28277980). In vitro, mediates the uptake of linear DNA more efficiently than that of circular DNA, but exhibits similar uptake efficacy toward RNA and DNA. Binds long double-stranded RNA (dsRNA) (500 - 700 base pairs), but not dsRNA shorter than 100 bp (By similarity).[UniProtKB:Q8CIF6]<ref>PMID:27046251</ref> <ref>PMID:27846365</ref> <ref>PMID:28277980</ref>
-[[Category: Ji, X]]
+== References ==
-[[Category: Qi, C]]
+<references/>
-[[Category: Sun, F]]
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Guo H]]
+[[Category: Ji X]]
+[[Category: Lu Y]]
+[[Category: Qi C]]
+[[Category: Sun F]]
+[[Category: Yang H]]
+[[Category: Zhu Y]]