8tbb: Difference between revisions

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OCA

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-'''Unreleased structure'''
-The entry 8tbb is ON HOLD
+==F9S, novel TIM-3 targeting antibody, bound to IgV domain of TIM-3==
+<StructureSection load='8tbb' size='340' side='right'caption='[[8tbb]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-Authors: Oganesyan, V., van Dyk, N., Mazor, Y., Yang, C.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8tbb]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TBB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TBB FirstGlance]. <br>
-Description: F9S, novel TIM-3 targeting antibody, bound to IgV domain of TIM-3
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8tbb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8tbb OCA], [https://pdbe.org/8tbb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8tbb RCSB], [https://www.ebi.ac.uk/pdbsum/8tbb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8tbb ProSAT]</span></td></tr>
-[[Category: Mazor, Y]]
+</table>
-[[Category: Oganesyan, V]]
+== Function ==
-[[Category: Yang, C]]
+[https://www.uniprot.org/uniprot/HAVR2_HUMAN HAVR2_HUMAN] Regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Receptor for LGALS9.<ref>PMID:14556005</ref> <ref>PMID:16286920</ref>
-[[Category: Van Dyk, N]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Mazor Y]]
+[[Category: Oganesyan V]]
+[[Category: Yang C]]
+[[Category: Van Dyk N]]