8ihm: Difference between revisions

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-'''Unreleased structure'''
-The entry 8ihm is ON HOLD
+==Eaf3 CHD domain bound to the nucleosome==
+<StructureSection load='8ihm' size='340' side='right'caption='[[8ihm]], [[Resolution|resolution]] 3.58&Aring;' scene=''>
-Authors: Zhang, Y.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8ihm]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] and [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8IHM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8IHM FirstGlance]. <br>
-Description: Eaf3 CHD domain bound to the nucleosome
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.58&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ML3:2-{[(2R)-2-AMINO-2-CARBOXYETHYL]SULFANYL}-N,N,N-TRIMETHYLETHANAMINIUM'>ML3</scene></td></tr>
-[[Category: Zhang, Y]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ihm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ihm OCA], [https://pdbe.org/8ihm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ihm RCSB], [https://www.ebi.ac.uk/pdbsum/8ihm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ihm ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/H32_XENLA H32_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Saccharomyces cerevisiae]]
+[[Category: Xenopus laevis]]
+[[Category: Gang C]]
+[[Category: Zhang Y]]