7z44: Difference between revisions
New page: '''Unreleased structure''' The entry 7z44 is ON HOLD Authors: Description: Category: Unreleased Structures |
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The | ==Portal of bacteriophage SU10== | ||
<StructureSection load='7z44' size='340' side='right'caption='[[7z44]], [[Resolution|resolution]] 3.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7z44]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_vB_EcoP_SU10 Escherichia phage vB_EcoP_SU10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Z44 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Z44 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.6Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7z44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7z44 OCA], [https://pdbe.org/7z44 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7z44 RCSB], [https://www.ebi.ac.uk/pdbsum/7z44 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7z44 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/A0A0B4N229_9CAUD A0A0B4N229_9CAUD] | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
Escherichia coli phage SU10 belongs to the genus Kuravirus from the class Caudoviricetes of phages with short non-contractile tails. In contrast to other short-tailed phages, the tails of Kuraviruses elongate upon cell attachment. Here we show that the virion of SU10 has a prolate head, containing genome and ejection proteins, and a tail, which is formed of portal, adaptor, nozzle, and tail needle proteins and decorated with long and short fibers. The binding of the long tail fibers to the receptors in the outer bacterial membrane induces the straightening of nozzle proteins and rotation of short tail fibers. After the re-arrangement, the nozzle proteins and short tail fibers alternate to form a nozzle that extends the tail by 28 nm. Subsequently, the tail needle detaches from the nozzle proteins and five types of ejection proteins are released from the SU10 head. The nozzle with the putative extension formed by the ejection proteins enables the delivery of the SU10 genome into the bacterial cytoplasm. It is likely that this mechanism of genome delivery, involving the formation of the tail nozzle, is employed by all Kuraviruses. | |||
Tail proteins of phage SU10 reorganize into the nozzle for genome delivery.,Siborova M, Fuzik T, Prochazkova M, Novacek J, Benesik M, Nilsson AS, Plevka P Nat Commun. 2022 Sep 24;13(1):5622. doi: 10.1038/s41467-022-33305-w. PMID:36153309<ref>PMID:36153309</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
[[Category: | </div> | ||
<div class="pdbe-citations 7z44" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[Portal protein 3D structures|Portal protein 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia phage vB_EcoP_SU10]] | |||
[[Category: Large Structures]] | |||
[[Category: Fuzik T]] | |||
[[Category: Novacek J]] | |||
[[Category: Plevka P]] | |||
[[Category: Prochazkova M]] | |||
[[Category: Siborova M]] | |||