7r1c: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-'''Unreleased structure'''
-The entry 7r1c is ON HOLD
+==Cryo-EM structure of Bacillus megaterium gas vesicles==
+<StructureSection load='7r1c' size='340' side='right'caption='[[7r1c]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7r1c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Priestia_megaterium_NBRC_15308_=_ATCC_14581 Priestia megaterium NBRC 15308 = ATCC 14581]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7R1C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7R1C FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7r1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7r1c OCA], [https://pdbe.org/7r1c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7r1c RCSB], [https://www.ebi.ac.uk/pdbsum/7r1c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7r1c ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/A0A0B6AAV2_PRIM2 A0A0B6AAV2_PRIM2] Gas vesicles are hollow, gas filled proteinaceous nanostructures found in some microorganisms. During planktonic growth they allow positioning of the organism at a favorable depth for light or nutrient acquisition. GvpA forms the protein shell.[HAMAP-Rule:MF_00576][RuleBase:RU000632]
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Gas vesicles are gas-filled nanocompartments that allow a diverse group of bacteria and archaea to control their buoyancy. The molecular basis of their properties and assembly remains unclear. Here, we report the 3.2 A cryo-EM structure of the gas vesicle shell made from the structural protein GvpA that self-assembles into hollow helical cylinders closed off by cone-shaped tips. Two helical half shells connect through a characteristic arrangement of GvpA monomers, suggesting a mechanism of gas vesicle biogenesis. The fold of GvpA features a corrugated wall structure typical for force-bearing thin-walled cylinders. Small pores enable gas molecules to diffuse across the shell, while the exceptionally hydrophobic interior surface effectively repels water. Comparative structural analysis confirms the evolutionary conservation of gas vesicle assemblies and demonstrates molecular features of shell reinforcement by GvpC. Our findings will further research into gas vesicle biology and facilitate molecular engineering of gas vesicles for ultrasound imaging.
-Authors:
+Cryo-EM structure of gas vesicles for buoyancy-controlled motility.,Huber ST, Terwiel D, Evers WH, Maresca D, Jakobi AJ Cell. 2023 Mar 2;186(5):975-986.e13. doi: 10.1016/j.cell.2023.01.041. PMID:36868215<ref>PMID:36868215</ref>
-Description:
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-[[Category: Unreleased Structures]]
+</div>
+<div class="pdbe-citations 7r1c" style="background-color:#fffaf0;"></div>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Priestia megaterium NBRC 15308 = ATCC 14581]]
+[[Category: Evers W]]
+[[Category: Huber ST]]
+[[Category: Jakobi AJ]]