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==Crystal structure of human TLR8 ectodomain bound to small molecule antagonist 21== | ==Crystal structure of human TLR8 ectodomain bound to small molecule antagonist 21== | ||
<StructureSection load='7rc9' size='340' side='right'caption='[[7rc9]]' scene=''> | <StructureSection load='7rc9' size='340' side='right'caption='[[7rc9]], [[Resolution|resolution]] 2.76Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RC9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RC9 FirstGlance]. <br> | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RC9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RC9 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rc9 OCA], [https://pdbe.org/7rc9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rc9 RCSB], [https://www.ebi.ac.uk/pdbsum/7rc9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rc9 ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.76Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=RQY:2-(2,6-dimethylpyridin-4-yl)-5-(piperidin-4-yl)-3-(propan-2-yl)-1H-indole'>RQY</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rc9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rc9 OCA], [https://pdbe.org/7rc9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rc9 RCSB], [https://www.ebi.ac.uk/pdbsum/7rc9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rc9 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
==See Also== | |||
*[[Toll-like Receptor 3D structures|Toll-like Receptor 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Critton DA]] | [[Category: Critton DA]] | ||
Latest revision as of 14:37, 30 October 2024
Crystal structure of human TLR8 ectodomain bound to small molecule antagonist 21Crystal structure of human TLR8 ectodomain bound to small molecule antagonist 21
Structural highlights
See Also |
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