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==Crystal Structure of IRAK4 kinase in complex with the inhibitor CA-4948== | ==Crystal Structure of IRAK4 kinase in complex with the inhibitor CA-4948== | ||
<StructureSection load='7c2v' size='340' side='right'caption='[[7c2v]]' scene=''> | <StructureSection load='7c2v' size='340' side='right'caption='[[7c2v]], [[Resolution|resolution]] 2.44Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7C2V OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7C2V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7C2V FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.44Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FJ0:2-(2-methylpyridin-4-yl)-N-[2-morpholin-4-yl-5-[(3R)-3-oxidanylpyrrolidin-1-yl]-[1,3]oxazolo[4,5-b]pyridin-6-yl]-1,3-oxazole-4-carboxamide'>FJ0</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7c2v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7c2v OCA], [https://pdbe.org/7c2v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7c2v RCSB], [https://www.ebi.ac.uk/pdbsum/7c2v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7c2v ProSAT]</span></td></tr> | |||
</table> | </table> | ||
==See Also== | |||
*[[Interleukin-1 receptor-associated kinase|Interleukin-1 receptor-associated kinase]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Latest revision as of 09:09, 21 November 2024
Crystal Structure of IRAK4 kinase in complex with the inhibitor CA-4948Crystal Structure of IRAK4 kinase in complex with the inhibitor CA-4948
Structural highlights
See Also |
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