Purine nucleoside phosphorylase 3D structures: Difference between revisions

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**[[1tcv]], [[1td1]], [[5cxs]], [[5cxq]] – SmPNP – ''Schistosoma mansoni''<br />
**[[1tcv]], [[1td1]], [[5cxs]], [[5cxq]] – SmPNP – ''Schistosoma mansoni''<br />
**[[2b94]] – PNP – ''Plasmodium knowlesi'' <br />
**[[2b94]] – PNP – ''Plasmodium knowlesi'' <br />
**[[4mar]] – MrPNP – ''Meiothermus ruber''<br />
**[[1vhj]] – VcPNP – ''Vibrio cholerae''<br />  
**[[1ecp]], [[1oty]], [[1ou4]], [[1yqq]], [[1yqu]], [[1yr3]], [[3onv]], [[4rj2]], [[4ts3]], [[4ts9]] – EcPNP – ''Escherichia coli'' <br />
**[[1otx]], [[1oum]], [[1ov6]], [[3opv]], [[4tta]], [[4tti]], [[4ttj]] – EcPNP (mutant)<br />
**[[1vhj]] – VcPNP – ''Vibrio cholerae''<br />
**[[1xe3]] – PNP – ''Bacillus anthracis''<br />
**[[4d8v]], [[4d8x]], [[4d8y]], [[4d98]] – BsPNP – ''Bacillus subtilis''<br />  
**[[3tl6]] – EhPNP – ''Entamoeba histolica''<br />
**[[3tl6]] – EhPNP – ''Entamoeba histolica''<br />
**[[3uav]], [[7fbg]] – BcPNP – ''Bacillus cereus''<br />
**[[4lkr]] – PNP – ''Shewanella oneidensis''<br />
**[[4tym]] – PNP – ''Streptococcus agalactiae'' <br />
**[[4tym]] – PNP – ''Streptococcus agalactiae'' <br />
**[[8d38]] – PNP – ''Geobacillus Stearothermophilus'' <br />
**[[8d38]] – PNP – ''Geobacillus Stearothermophilus'' <br />
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**[[1tcu]] – SmPNP + phosphate <br />
**[[1tcu]] – SmPNP + phosphate <br />
**[[3khs]] – PNP + phosphate – grouper iridovirus<br />
**[[3khs]] – PNP + phosphate – grouper iridovirus<br />
**[[4m3n]] – MrPNP + phosphate <br />
**[[3ooe]], [[3ooh]] – EcPNP + phosphate <br />
**[[4ldn]] – PNP + phosphate – ''Vibrio fischeri''<br />
**[[4ldn]] – PNP + phosphate – ''Vibrio fischeri''<br />
**[[4m7w]] – PNP + phosphate – ''Leptotrichia buccalis''<br />
**[[4m7w]] – PNP + phosphate – ''Leptotrichia buccalis''<br />
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**[[3iex]] – SmPNP + guanosine<br />
**[[3iex]] – SmPNP + guanosine<br />
**[[1odj]] – TtPNP + guanosine<br />
**[[1odj]] – TtPNP + guanosine<br />
**[[4da0]], [[4da8]], [[4dae]] – BsPNP + guanosine derivative<br />
**[[1vmk]] – PNP + guanine – ''Thermotoga maritima'' <br />
**[[1vmk]] – PNP + guanine – ''Thermotoga maritima'' <br />
**[[3iom]] – MtPNP + guanine derivative - ''Mycobacterium tuberculosis'' <br />
**[[3iom]] – MtPNP + guanine derivative - ''Mycobacterium tuberculosis'' <br />
**[[5i3c]] - EcPNP + guanine derivative <br />
**[[1c3x]] – CePNP + guanine derivative + phosphate<br />
**[[1c3x]] – CePNP + guanine derivative + phosphate<br />


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**[[5tbt]] – SmPNP + cytidine <br />
**[[5tbt]] – SmPNP + cytidine <br />
**[[1z38]] – TvPNP + inosine <br />
**[[1z38]] – TvPNP + inosine <br />
**[[3uax]] – BcPNP + inosine <br />
**[[1z39]] – TvPNP + deoxyinosine <br />
**[[2bsx]] – PfPNP + inosine <br />
**[[2bsx]] – PfPNP + inosine <br />
**[[1z39]] – TvPNP + deoxyinosine <br />
**[[1pr0]] - EcPNP + inosine + phosphate<br />


*Purine nucleoside phosphorylase complex with xanthine and xanthine derivatives
*Purine nucleoside phosphorylase complex with xanthine and xanthine derivatives
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**[[3bgs]] – bPNP + transition state analog + phosphate<br />
**[[3bgs]] – bPNP + transition state analog + phosphate<br />
**[[3fnq]], [[5tbu]] – SmPNP + hypoxanthine<br />
**[[3fnq]], [[5tbu]] – SmPNP + hypoxanthine<br />
**[[4dab]] – BsPNP + hypoxanthine<br />
**[[4uc0]] – PNP + hypoxanthine – ''Agrobacterium vitis''<br />
**[[4uc0]] – PNP + hypoxanthine – ''Agrobacterium vitis''<br />
**[[5ifk]] - PNP + hypoxanthine - ''Kluyveromyces lactis''<br />
**[[5ifk]] - PNP + hypoxanthine - ''Kluyveromyces lactis''<br />
**[[3enz]] – PfPNP + hypoxanthine + ribose + arsenate<br />
**[[3enz]] – PfPNP + hypoxanthine + ribose + arsenate<br />
**[[5iu6]] - EcPNP + hypoxanthine derivative<br />
**[[3odg]] – YpPNP + xanthine – ''Yersinia pseudotuberculosis''<br />
**[[3odg]] – YpPNP + xanthine – ''Yersinia pseudotuberculosis''<br />
**[[3mb8]] – PNP + transition state analog + phosphate – ''Toxoplasma gondii''<br />
**[[3mb8]] – PNP + transition state analog + phosphate – ''Toxoplasma gondii''<br />
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**[[3u40]] – EhPNP + adenosine <br />
**[[3u40]] – EhPNP + adenosine <br />
**[[4d9h]] – BsPNP + adenosine <br />
**[[4d9h]] – BsPNP + adenosine <br />
**[[4dan]] – BsPNP + adenosine derivative<br />
**[[2ac7]], [[3uaw]] – BcPNP + adenosine <br />
**[[3uay]], [[3uaz]] – BcPNP (mutant) + adenosine <br />
**[[4m1e]] – PNP + adenine – ''Planctomyces limnophilus''<br />
**[[4m1e]] – PNP + adenine – ''Planctomyces limnophilus''<br />
**[[4lna]] – PNP + adenine + phosphate – ''Spirosoma linguale''<br />
**[[4lna]] – PNP + adenine + phosphate – ''Spirosoma linguale''<br />
**[[1pk7]] - EcPNP + adenosine + phosphate<br />
**[[1pk9]], [[1pke]], [[1pr5]], [[1pr6]], [[1pw7]] - EcPNP + adenosine derivative + phosphate<br />


*Purine nucleoside phosphorylase complex with purine and purine derivatives
*Purine nucleoside phosphorylase complex with purine and purine derivatives
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**[[1lv8]], [[1lvu]], [[2qpl]] – bPNP + purine derivative <br />
**[[1lv8]], [[1lvu]], [[2qpl]] – bPNP + purine derivative <br />
**[[1fxu]] – bPNP + purine derivative + phosphate<br />
**[[1fxu]] – bPNP + purine derivative + phosphate<br />
**[[1ovg]] - EcPNP (mutant) + purine derivative <br />
**[[1pr2]], [[1pr4]] – EcPNP + purine derivative + phosphate<br />


*Other purine nucleoside phosphorylase complexes
*Other purine nucleoside phosphorylase complexes


**[[3d1v]] – hPNP + mercapto-quinazolinone<br />
**[[3d1v]] – hPNP + mercapto-quinazolinone<br />
**[[7zsl]], [[7zsm]], [[7zsn]], [[7zso, [[7zsp]], [[7zsq]], [[7zsr]] – hPNP + inhibitor<br />
**[[7zsl]], [[7zsm]], [[7zsn]], [[7zso]], [[7zsp]], [[7zsq]], [[7zsr]] – hPNP + inhibitor<br />
**[[5etj]], [[5ugf]] - hPNP (mutant) + inhibitor + phosphate<br />
**[[5etj]], [[5ugf]] - hPNP (mutant) + inhibitor + phosphate<br />
**[[1z36]] – TvPNP + antibiotic<br />
**[[1z36]] – TvPNP + antibiotic<br />
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**[[5ko5]] - SmPNP + cytosine<br />
**[[5ko5]] - SmPNP + cytosine<br />
**[[5ko6]] - SmPNP + cytosine + ribose-1-phosphate<br />
**[[5ko6]] - SmPNP + cytosine + ribose-1-phosphate<br />
**[[1a69]], [[1pr1]] – EcPNP + formycin <br />
**[[1k9s]], [[3ut6]] – EcPNP + formycin derivative + phosphate<br />
**[[7f3v]], [[7w1g]] – EcPNP (mutant) + UDP derivative + phosphate<br />
**[[3fow]], [[6aqs]] – PfPNP (mutant) + inhibitor + phosphate<br />
**[[3fow]], [[6aqs]] – PfPNP (mutant) + inhibitor + phosphate<br />
**[[5znc]], [[5zni]] – PfPNP + quinine derivative + phosphate<br />
**[[5znc]], [[5zni]] – PfPNP + quinine derivative + phosphate<br />
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**[[3occ]] – YpPNP + inhibitor + phosphate<br />
**[[3occ]] – YpPNP + inhibitor + phosphate<br />
**[[3of3]] – VcPNP + inhibitor + phosphate<br />
**[[3of3]] – VcPNP + inhibitor + phosphate<br />
**[[4da6]], [[4da7]], [[4dar]] – BsPNP + drug<br />
**[[3ix2]] – MtPNP + drug<br />
**[[3ix2]] – MtPNP + drug<br />
**[[8c25]] – MtPNP + inhibitor<br />
**[[8c25]] – MtPNP + inhibitor<br />
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**[[6f4w]], [[6f4x]], [[6f52]] – HpPNP + formycin <br />
**[[6f4w]], [[6f4x]], [[6f52]] – HpPNP + formycin <br />
**[[7ooy]], [[7ooz]], [[7op9]], [[7opa]] – HpPNP + purine derivative <br />
**[[7ooy]], [[7ooz]], [[7op9]], [[7opa]] – HpPNP + purine derivative <br />
**[[1ecp]], [[1oty]], [[1ou4]], [[1yqq]], [[1yqu]], [[1yr3]], [[3onv]], [[4rj2]], [[4ts3]], [[4ts9]] – EcPNP – ''Escherichia coli'' <br />
**[[1otx]], [[1oum]], [[1ov6]], [[3opv]], [[4tta]], [[4tti]], [[4ttj]] – EcPNP (mutant)<br />
**[[1a69]], [[1pr1]] – EcPNP + formycin <br />
**[[6xz2]] – EcPNP (mutant) + formycin <br />
**[[6xz2]] – EcPNP (mutant) + formycin <br />
**[[1pr0]] - EcPNP + inosine + phosphate<br />
**[[5i3c]] - EcPNP + guanine derivative <br />
**[[5iu6]] - EcPNP + hypoxanthine derivative<br />
**[[1pk7]] - EcPNP + adenosine + phosphate<br />
**[[1pk9]], [[1pke]], [[1pr5]], [[1pr6]], [[1pw7]] - EcPNP + adenosine derivative + phosphate<br />
**[[1ovg]] - EcPNP (mutant) + purine derivative <br />
**[[1pr2]], [[1pr4]] – EcPNP + purine derivative + phosphate<br />
**[[1k9s]], [[3ut6]] – EcPNP + formycin derivative + phosphate<br />
**[[7f3v]], [[7w1g]] – EcPNP (mutant) + UDP derivative + phosphate<br />
**[[3ooe]], [[3ooh]] – EcPNP + phosphate <br />
**[[1xe3]] – PNP – ''Bacillus anthracis''<br />
**[[4lkr]] – PNP – ''Shewanella oneidensis''<br />
**[[3uav]], [[7fbg]] – BcPNP – ''Bacillus cereus''<br />
**[[3uax]] – BcPNP + inosine <br />
**[[2ac7]], [[3uaw]] – BcPNP + adenosine <br />
**[[3uay]], [[3uaz]] – BcPNP (mutant) + adenosine <br />
**[[4d8v]], [[4d8x]], [[4d8y]], [[4d98]] – BsPNP – ''Bacillus subtilis''<br />
**[[4da0]], [[4da8]], [[4dae]] – BsPNP + guanosine derivative<br />
**[[4dab]] – BsPNP + hypoxanthine<br />
**[[4dao]] – BsPNP + adenine <br />
**[[4da6]], [[4da7]], [[4dar]] – BsPNP + drug<br />
**[[4mar]] – MrPNP – ''Meiothermus ruber''<br />
**[[4m3n]] – MrPNP + phosphate <br />
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Michal Harel