6pt0: Difference between revisions

<SX load='6pt0' size='340' side='right' viewer='molstar' caption='[[6pt0]], [[Resolution|resolution]] 3.20&Aring;' scene=''>

<table><tr><td colspan='2'>[[6pt0]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PT0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PT0 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene>, <scene name='pdbligand=WI5:{(3R)-5-methyl-3-[(morpholin-4-yl)methyl]-2,3-dihydro[1,4]oxazino[2,3,4-hi]indol-6-yl}(naphthalen-1-yl)methanone'>WI5</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pt0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pt0 OCA], [https://pdbe.org/6pt0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pt0 RCSB], [https://www.ebi.ac.uk/pdbsum/6pt0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pt0 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref>  

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[[Category: Homo sapiens]]

[[Category: Synthetic construct]]

[[Category: Chen M]]

[[Category: Feng Z]]

[[Category: Liu H]]

[[Category: McGuire T]]

[[Category: Melcher K]]

[[Category: Meng X]]

[[Category: Wang J]]

[[Category: Wang L]]

[[Category: Xie XQ]]

[[Category: Xing C]]

[[Category: Xu HE]]

[[Category: Xu TH]]

[[Category: Xue Y]]

[[Category: Zhang C]]

[[Category: Zhao G]]

[[Category: Zhou XE]]

[[Category: Zhuang Y]]