6pd9: Difference between revisions

<table><tr><td colspan='2'>[[6pd9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PD9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PD9 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=O9G:2-fluoranyl-3-methyl-~{N}-(phenylsulfonyl)-5-pyrazol-1-yl-benzohydrazide'>O9G</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pd9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pd9 OCA], [https://pdbe.org/6pd9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pd9 RCSB], [https://www.ebi.ac.uk/pdbsum/6pd9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pd9 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/KAT8_HUMAN KAT8_HUMAN] Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM. As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. That activity is less specific than the one of the MSL complex.<ref>PMID:12397079</ref> <ref>PMID:15923642</ref> <ref>PMID:20018852</ref>  

[[Category: Homo sapiens]]

[[Category: Baell JB]]

[[Category: Hermans SJ]]

[[Category: Parker MW]]

[[Category: Thomas T]]