6np0: Difference between revisions

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<SX load='6np0' size='340' side='right' viewer='molstar' caption='[[6np0]], [[Resolution|resolution]] 2.92&Aring;' scene=''>
<SX load='6np0' size='340' side='right' viewer='molstar' caption='[[6np0]], [[Resolution|resolution]] 2.92&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6np0]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NP0 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6NP0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6np0]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NP0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6NP0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CWB:1-METHYL-N-[(1R,5S)-9-METHYL-9-AZABICYCLO[3.3.1]NONAN-3-YL]INDAZOLE-3-CARBOXAMIDE'>CWB</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.92&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Htr3a ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CWB:1-METHYL-N-[(1R,5S)-9-METHYL-9-AZABICYCLO[3.3.1]NONAN-3-YL]INDAZOLE-3-CARBOXAMIDE'>CWB</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6np0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6np0 OCA], [http://pdbe.org/6np0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6np0 RCSB], [http://www.ebi.ac.uk/pdbsum/6np0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6np0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6np0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6np0 OCA], [https://pdbe.org/6np0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6np0 RCSB], [https://www.ebi.ac.uk/pdbsum/6np0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6np0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/5HT3A_MOUSE 5HT3A_MOUSE] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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<div class="pdbe-citations 6np0" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6np0" style="background-color:#fffaf0;"></div>
==See Also==
*[[5-hydroxytryptamine receptor 3D structures|5-hydroxytryptamine receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Basak, S]]
[[Category: Basak S]]
[[Category: Chakrapani, S]]
[[Category: Chakrapani S]]
[[Category: Membrane protein]]

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