6hr9: Difference between revisions

New page: '''Unreleased structure''' The entry 6hr9 is ON HOLD until Paper Publication Authors: Bellini, D., Dowson, C.G. Description: Nitrocefin acylation of both catalytic serines of the Y409 ...
 
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'''Unreleased structure'''


The entry 6hr9 is ON HOLD  until Paper Publication
==Nitrocefin acylation of both catalytic serines of the Y409 mutant of penicillin-binding protein 3 from P. aeruginosa==
<StructureSection load='6hr9' size='340' side='right'caption='[[6hr9]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6hr9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HR9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6HR9 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.99&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NEF:(2~{R})-5-[(~{E})-2-(2,4-dinitrophenyl)ethenyl]-2-[(1~{R})-2-oxidanyl-2-oxidanylidene-1-(2-thiophen-2-ylethanoylamino)ethyl]-3,6-dihydro-2~{H}-1,3-thiazine-4-carboxylic+acid'>NEF</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6hr9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hr9 OCA], [https://pdbe.org/6hr9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6hr9 RCSB], [https://www.ebi.ac.uk/pdbsum/6hr9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6hr9 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FTSI_PSEAE FTSI_PSEAE] Catalyzes cross-linking of the peptidoglycan cell wall at the division septum (By similarity). Binds penicillin (PubMed:20580675).[HAMAP-Rule:MF_02080]<ref>PMID:20580675</ref>


Authors: Bellini, D., Dowson, C.G.
==See Also==
 
*[[Penicillin-binding protein 3D structures|Penicillin-binding protein 3D structures]]
Description: Nitrocefin acylation of both catalytic serines of the Y409 mutant of penicillin-binding protein 3 from P. aeruginosa
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Bellini, D]]
__TOC__
[[Category: Dowson, C.G]]
</StructureSection>
[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa PAO1]]
[[Category: Bellini D]]
[[Category: Dowson CG]]

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