6mb3: Difference between revisions

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 ==Cryo-EM structure of the circumsporozoite protein of Plasmodium falciparum with a vaccine-elicited antibody reveals maturation of inter-antibody contacts==
-<StructureSection load='6mb3' size='340' side='right' caption='[[6mb3]], [[Resolution|resolution]] 3.37&Aring;' scene=''>
+<SX load='6mb3' size='340' side='right' viewer='molstar' caption='[[6mb3]], [[Resolution|resolution]] 3.37&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[6mb3]] is a 19 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MB3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MB3 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6mb3]] is a 19 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MB3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6MB3 FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6mb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mb3 OCA], [http://pdbe.org/6mb3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6mb3 RCSB], [http://www.ebi.ac.uk/pdbsum/6mb3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6mb3 ProSAT]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.37&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6mb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mb3 OCA], [https://pdbe.org/6mb3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6mb3 RCSB], [https://www.ebi.ac.uk/pdbsum/6mb3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6mb3 ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/CSP_PLAF7 CSP_PLAF7] Essential sporozoite protein (PubMed:29554084, PubMed:32150583). In the mosquito vector, required for sporozoite development in the oocyst, migration through the vector hemolymph and entry into the vector salivary glands (By similarity). In the vertebrate host, required for sporozoite migration through the host dermis and infection of host hepatocytes (PubMed:29554084, PubMed:32150583). Binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes (By similarity).[UniProtKB:P23093]<ref>PMID:29554084</ref> <ref>PMID:32150583</ref>   In the vertebrate host, binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes and is required for sporozoite invasion of the host hepatocytes.[UniProtKB:P23093]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 15: / Line 18: @@
 </div>
 <div class="pdbe-citations 6mb3" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
 == References ==
 <references/>
 __TOC__
-</StructureSection>
+</SX>
-[[Category: Cottrell, C A]]
+[[Category: Homo sapiens]]
-[[Category: Torres, J L]]
+[[Category: Large Structures]]
-[[Category: Ward, A B]]
-[[Category: Antibody]]
-[[Category: Csp]]
-[[Category: Immune system]]
 [[Category: Plasmodium falciparum]]
-[[Category: Rscsp]]
+[[Category: Cottrell CA]]
+[[Category: Torres JL]]
+[[Category: Ward AB]]