6drv: Difference between revisions
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New page: '''Unreleased structure''' The entry 6drv is ON HOLD Authors: Cianfrocco, M.A., Lahiri, I., DiMaio, F., Leschziner, A.E. Description: Beta-galactosidase [[Category: Unreleased Structur... |
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==Beta-galactosidase== | |||
<SX load='6drv' size='340' side='right' viewer='molstar' caption='[[6drv]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6drv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DRV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DRV FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.2Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6drv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6drv OCA], [https://pdbe.org/6drv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6drv RCSB], [https://www.ebi.ac.uk/pdbsum/6drv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6drv ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/BGAL_ECOLI BGAL_ECOLI] | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
Access to streamlined computational resources remains a significant bottleneck for new users of cryo-electron microscopy (cryo-EM). To address this, we have developed tools that will submit cryo-EM analysis routines and atomic model building jobs directly to Amazon Web Services (AWS) from a local computer or laptop. These new software tools ("cryoem-cloud-tools") have incorporated optimal data movement, security, and cost-saving strategies, giving novice users access to complex cryo-EM data processing pipelines. Integrating these tools into the RELION processing pipeline and graphical user interface we determined a 2.2A structure of ss-galactosidase in approximately 55h on AWS. We implemented a similar strategy to submit Rosetta atomic model building and refinement to AWS. These software tools dramatically reduce the barrier for entry of new users to cloud computing for cryo-EM and are freely available at cryoem-tools.cloud. | |||
cryoem-cloud-tools: A software platform to deploy and manage cryo-EM jobs in the cloud.,Cianfrocco MA, Lahiri I, DiMaio F, Leschziner AE J Struct Biol. 2018 Jun 1. pii: S1047-8477(18)30138-2. doi:, 10.1016/j.jsb.2018.05.014. PMID:29864529<ref>PMID:29864529</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
[[Category: | </div> | ||
[[Category: | <div class="pdbe-citations 6drv" style="background-color:#fffaf0;"></div> | ||
[[Category: | |||
[[Category: Lahiri | ==See Also== | ||
[[Category: | *[[Galactosidase 3D structures|Galactosidase 3D structures]] | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</SX> | |||
[[Category: Escherichia coli K-12]] | |||
[[Category: Large Structures]] | |||
[[Category: Cianfrocco MA]] | |||
[[Category: DiMaio F]] | |||
[[Category: Lahiri I]] | |||
[[Category: Leschziner AE]] | |||
Latest revision as of 12:51, 23 October 2024
Beta-galactosidaseBeta-galactosidase
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