6a78: Difference between revisions

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 ==Crystal structure of the fifth immunoglobulin domain (Ig5) of human Robo1 in complex with the scFv fragment of murine monoclonal antibody B5209B==
-<StructureSection load='6a78' size='340' side='right' caption='[[6a78]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
+<StructureSection load='6a78' size='340' side='right'caption='[[6a78]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[6a78]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6A78 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6A78 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6a78]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6A78 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6A78 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6a78 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6a78 OCA], [http://pdbe.org/6a78 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6a78 RCSB], [http://www.ebi.ac.uk/pdbsum/6a78 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6a78 ProSAT]</span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6a78 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6a78 OCA], [https://pdbe.org/6a78 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6a78 RCSB], [https://www.ebi.ac.uk/pdbsum/6a78 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6a78 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/ROBO1_HUMAN ROBO1_HUMAN]] Receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. May be required for lung development.<ref>PMID:10102268</ref>
+[https://www.uniprot.org/uniprot/ROBO1_HUMAN ROBO1_HUMAN] Receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. May be required for lung development.<ref>PMID:10102268</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 18: / Line 19: @@
 </div>
 <div class="pdbe-citations 6a78" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Inoue, T]]
+[[Category: Homo sapiens]]
-[[Category: Kado, Y]]
+[[Category: Large Structures]]
-[[Category: Mizohata, E]]
+[[Category: Mus musculus]]
-[[Category: Nakayama, T]]
+[[Category: Inoue T]]
-[[Category: Angiogenesis]]
+[[Category: Kado Y]]
-[[Category: Antibody drug]]
+[[Category: Mizohata E]]
-[[Category: Hepatocellular carcinoma antigen]]
+[[Category: Nakayama T]]
-[[Category: Immune system]]
-[[Category: Single chain fv fragment]]