6f8b: Difference between revisions

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==LasB bound to thiol based inhibitor==
==LasB bound to thiol based inhibitor==
<StructureSection load='6f8b' size='340' side='right' caption='[[6f8b]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
<StructureSection load='6f8b' size='340' side='right'caption='[[6f8b]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6f8b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F8B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6F8B FirstGlance]. <br>
<table><tr><td colspan='2'>[[6f8b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6F8B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6F8B FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CXH:~{N}-(3,4-dichlorophenyl)-2-sulfanyl-ethanamide'>CXH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pseudolysin Pseudolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.26 3.4.24.26] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CXH:~{N}-(3,4-dichlorophenyl)-2-sulfanyl-ethanamide'>CXH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6f8b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f8b OCA], [http://pdbe.org/6f8b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6f8b RCSB], [http://www.ebi.ac.uk/pdbsum/6f8b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6f8b ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6f8b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6f8b OCA], [https://pdbe.org/6f8b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6f8b RCSB], [https://www.ebi.ac.uk/pdbsum/6f8b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6f8b ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ELAS_PSEAE ELAS_PSEAE] Cleaves elastin, collagen, IgG, and several complement components. Involved in the pathogenesis of P.aeruginosa infections.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Elastase|Elastase]]
*[[Elastase 3D structures|Elastase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Pseudolysin]]
[[Category: Large Structures]]
[[Category: Koehnke, J]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Sikandar, A]]
[[Category: Koehnke J]]
[[Category: Hydrolase]]
[[Category: Sikandar A]]
[[Category: Inhibitor]]
[[Category: Lasb]]

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