5xf1: Difference between revisions

<StructureSection load='5xf1' size='340' side='right'caption='[[5xf1]], [[Resolution|resolution]] 3.19&Aring;' scene=''>

<table><tr><td colspan='2'>[[5xf1]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XF1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XF1 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.19&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=97V:4-{[(4-CYCLOHEXYLPHENYL){[3-(METHYLSULFONYL)PHENYL]CARBAMOYL}AMINO]METHYL}-N-(1H-TETRAZOL-5-YL)BENZAMIDE'>97V</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xf1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xf1 OCA], [https://pdbe.org/5xf1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xf1 RCSB], [https://www.ebi.ac.uk/pdbsum/5xf1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xf1 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref> [https://www.uniprot.org/uniprot/GLR_HUMAN GLR_HUMAN] This is a receptor for glucagon which plays a central role in regulating the level of blood glucose by controlling the rate of hepatic glucose production and insulin secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.

[[Category: Escherichia virus T4]]

[[Category: Large Structures]]

[[Category: Cai X]]

[[Category: Cherezov V]]

[[Category: Dai A]]

[[Category: Dharmarajan V]]

[[Category: Dong Y]]

[[Category: Geng Z]]

[[Category: Grant T]]

[[Category: Griffin P]]

[[Category: Han GW]]

[[Category: Hanson M]]

[[Category: Jiang H]]

[[Category: Lau J]]

[[Category: Lin G]]

[[Category: Liu W]]

[[Category: Ma L]]

[[Category: Nelson G]]

[[Category: Qiao A]]

[[Category: Reedtz-Runge S]]

[[Category: Sierra R]]

[[Category: Song G]]

[[Category: Stevens R]]

[[Category: Wang M]]

[[Category: Weierstall U]]

[[Category: Wu B]]

[[Category: Wu X]]

[[Category: Wu Y]]

[[Category: Yang D]]

[[Category: Yang H]]

[[Category: Yang L]]

[[Category: Zhang H]]

[[Category: Zhao Q]]

[[Category: De Graaf C]]