5neu: Difference between revisions

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OCA

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 <SX load='5neu' size='340' side='right' viewer='molstar' caption='[[5neu]], [[Resolution|resolution]] 12.30&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[5neu]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Fmdv Fmdv] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NEU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NEU FirstGlance]. <br>
+<table><tr><td colspan='2'>[[5neu]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Foot-and-mouth_disease_virus Foot-and-mouth disease virus] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NEU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NEU FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 12.3&#8491;</td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ITGAV, MSK8, VNRA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), ITGB6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5neu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5neu OCA], [http://pdbe.org/5neu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5neu RCSB], [http://www.ebi.ac.uk/pdbsum/5neu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5neu ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5neu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5neu OCA], [https://pdbe.org/5neu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5neu RCSB], [https://www.ebi.ac.uk/pdbsum/5neu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5neu ProSAT]</span></td></tr>
 </table>
-== Disease ==
-[[http://www.uniprot.org/uniprot/ITB6_HUMAN ITB6_HUMAN]] Hypocalcified amelogenesis imperfecta;Hypoplastic amelogenesis imperfecta.
 == Function ==
-[[http://www.uniprot.org/uniprot/ITB6_HUMAN ITB6_HUMAN]] Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion.<ref>PMID:17545607</ref>  [[http://www.uniprot.org/uniprot/ITAV_HUMAN ITAV_HUMAN]] The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
+[https://www.uniprot.org/uniprot/D1H101_9PICO D1H101_9PICO]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
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 __TOC__
 </SX>
-[[Category: Fmdv]]
+[[Category: Foot-and-mouth disease virus]]
-[[Category: Human]]
+[[Category: Homo sapiens]]
 [[Category: Large Structures]]
-[[Category: Kotecha, A]]
+[[Category: Kotecha A]]
-[[Category: Stuart, D]]
+[[Category: Stuart D]]
-[[Category: Complex]]
-[[Category: Foot and mouth disease virus]]
-[[Category: Opanasia]]
-[[Category: Virus]]
-[[Category: Virus-receptor]]