5bzr: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| (2 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule== | ==Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule== | ||
<StructureSection load='5bzr' size='340' side='right' caption='[[5bzr]], [[Resolution|resolution]] 1.15Å' scene=''> | <StructureSection load='5bzr' size='340' side='right'caption='[[5bzr]], [[Resolution|resolution]] 1.15Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5bzr]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BZR OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[5bzr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BZR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BZR FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4XM:2-[3-(TETRAHYDRO-2H-PYRAN-4-YLOXY)PROPYL]-1,2,3,4-TETRAHYDROISOQUINOLIN-8-AMINE'>4XM</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.15Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4XM:2-[3-(TETRAHYDRO-2H-PYRAN-4-YLOXY)PROPYL]-1,2,3,4-TETRAHYDROISOQUINOLIN-8-AMINE'>4XM</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bzr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bzr OCA], [https://pdbe.org/5bzr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bzr RCSB], [https://www.ebi.ac.uk/pdbsum/5bzr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bzr ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/CD44_MOUSE CD44_MOUSE] Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing. | ||
==See Also== | |||
*[[CD44|CD44]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mus musculus]] | ||
[[Category: | [[Category: Finzel BC]] | ||
[[Category: | [[Category: Liu LK]] | ||
Latest revision as of 06:54, 21 November 2024
Crystal structure of the murine cd44 hyaluronan binding domain complex with a small moleculeCrystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule
Structural highlights
FunctionCD44_MOUSE Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing. See Also |
| ||||||||||||||||||