4y1x: Difference between revisions
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==Complex of human Galectin-1 and Galbeta1-4(6OSO3)GlcNAc== | |||
<StructureSection load='4y1x' size='340' side='right'caption='[[4y1x]], [[Resolution|resolution]] 2.45Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4y1x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Y1X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4Y1X FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6S2:METHYL+2-(ACETYLAMINO)-2-DEOXY-6-O-SULFO-BETA-D-GLUCOPYRANOSIDE'>6S2</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4y1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4y1x OCA], [https://pdbe.org/4y1x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4y1x RCSB], [https://www.ebi.ac.uk/pdbsum/4y1x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4y1x ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/LEG1_HUMAN LEG1_HUMAN] May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.<ref>PMID:14617626</ref> <ref>PMID:18796645</ref> | |||
==See Also== | |||
*[[Galectin 3D structures|Galectin 3D structures]] | |||
== References == | |||
[[Category: | <references/> | ||
[[Category: Hsieh | __TOC__ | ||
[[Category: Lin | </StructureSection> | ||
[[Category: Lin | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | |||
[[Category: Hsieh TJ]] | |||
[[Category: Lin CH]] | |||
[[Category: Lin HY]] |