Invertase: Difference between revisions
Michal Harel (talk | contribs) New page: <StructureSection load='3kf3' size='340' side='right' caption='Invertase complex with fructose (PDB code 3kf3).' scene=''> == Function == '''Invertase''' (INV) catalyzes the hydroly... |
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<StructureSection load='1w2t' size='350' side='right' caption='Invertase complex with raffinose (stick model), citrate and sulfate (PDB code [[1w2t]]).' scene=''> | |||
<StructureSection load=' | |||
== Function == | == Function == | ||
'''Invertase''' (INV) catalyzes the hydrolysis of sucrose into glucose and | '''Invertase''' (INV) catalyzes the hydrolysis of sucrose into glucose and fructose<ref>PMID:4963242</ref>. INV is produced by bees which use it to make honey from nectar. | ||
*'''Cell-wall INV''' is crucial for metabolism, growth and differentiation in plants<ref>PMID:24646208</ref>. | |||
*'''Extracellular INV''' catalyzes the cleavage of the transport sugar sucrose released into the app-last<ref>PMID:12508062</ref> | |||
*'''Alkaline INV''' is a tetramer which catalyzes the cleavage of sucrose<ref>PMID:8972597</ref> | |||
*'''DNA INV Gin''' is found in bacteriophage Mu and catalyses the recombination between repeat sequences in vivo and in vitro<ref>PMID:3042382</ref> | |||
For details in Hebrew see [[Invertase (Hebrew)]]. | |||
== Relevance == | == Relevance == | ||
INV is used in the food industry to produce fructose which is sweeter and does not crystallize easily. | |||
== Structural highlights == | == Structural highlights == | ||
The <scene name='67/676994/Cv/7'>active site pocket</scene> of INV contains the catalytic residues Asp and Glu<ref>PMID:16411890</ref>. | |||
</StructureSection> | </StructureSection> | ||
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*Invertase | *Invertase | ||
**[[4eqv]] – INV 2 – yeast<br /> | |||
**[[1uyp]] – TmINV – ''Thermotoga maritima''<br /> | **[[1uyp]] – TmINV – ''Thermotoga maritima''<br /> | ||
**[[ | **[[1w2t]] – TmINV (mutant) + trisaccharide<br /> | ||
**[[3kf5]] – SoINV – ''Schwanniomyces occidentalis''<br /> | **[[3kf5]] – SoINV – ''Schwanniomyces occidentalis''<br /> | ||
**[[3kf3]] – SoINV + fructose <br /> | **[[3kf3]] – SoINV + fructose <br /> | ||
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**[[2oxb]], [[2qqu]], [[2qqv]], [[2qqw]] – AtINV (mutant) + sucrose<br /> | **[[2oxb]], [[2qqu]], [[2qqv]], [[2qqw]] – AtINV (mutant) + sucrose<br /> | ||
**[[2xqr]] – AtINV + INV inhibitor <br /> | **[[2xqr]] – AtINV + INV inhibitor <br /> | ||
**[[6ttj]] – AtINV 2<br /> | |||
*Alkaline invertase | |||
**[[5gor]], [[5z73]] – AnINV – ''Anabaena''<br /> | |||
**[[5goo]], [[5gop]], [[5goq]] – AnINV + sugar <br /> | |||
*DNA-invertase | |||
**[[3uj3]] – muINV – enterobacteria phage mu<br /> | |||
**[[4m6f]] – muINV + DNA <br /> | |||
*Extracellular invertase | |||
**[[5xh8]], [[5xh9]] – moINV – mold<br /> | |||
**[[5xha]] – moINV + fructose<br /> | |||
}} | }} | ||