4wrc: Difference between revisions

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-'''Unreleased structure'''
-The entry 4wrc is ON HOLD  until Paper Publication
+==Crystal Structure of Surfactant Protein-A DEDN Mutant (E171D/P175E/R197N/K203D)==
+<StructureSection load='4wrc' size='340' side='right'caption='[[4wrc]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-Authors: Rynkiewicz, M.J., Wu, H., Cafarella, T.R., Nikolaidis, N.M., Head, J.F., Seaton, B.A., McCormack, F.X.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4wrc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WRC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WRC FirstGlance]. <br>
-Description: Crystal Structure of Surfactant Protein-A DEDN Mutant (E171D/P175E/R197N/K203D)
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HEZ:HEXANE-1,6-DIOL'>HEZ</scene></td></tr>
-[[Category: Mccormack, F.X]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wrc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wrc OCA], [https://pdbe.org/4wrc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wrc RCSB], [https://www.ebi.ac.uk/pdbsum/4wrc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wrc ProSAT]</span></td></tr>
-[[Category: Cafarella, T.R]]
+</table>
-[[Category: Nikolaidis, N.M]]
+== Function ==
-[[Category: Wu, H]]
+[https://www.uniprot.org/uniprot/SFTPA_RAT SFTPA_RAT] In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.
-[[Category: Rynkiewicz, M.J]]
+__TOC__
-[[Category: Head, J.F]]
+</StructureSection>
-[[Category: Seaton, B.A]]
+[[Category: Large Structures]]
+[[Category: Rattus norvegicus]]
+[[Category: Cafarella TR]]
+[[Category: Head JF]]
+[[Category: McCormack FX]]
+[[Category: Nikolaidis NM]]
+[[Category: Rynkiewicz MJ]]
+[[Category: Seaton BA]]
+[[Category: Wu H]]