Tumor necrosis factor receptor: Difference between revisions
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== Function == | == Function == | ||
'''Tumor necrosis factor receptor''' (TNFR) or '''death receptor''' is a trimeric cytokine receptor which binds TNF<ref>PMID:10358762</ref>. TNFR family contains several members and superfamily (TNFRSF) members. <br /> | '''Tumor necrosis factor receptor''' (TNFR) or '''death receptor''' is a trimeric cytokine receptor which binds TNF<ref>PMID:10358762</ref>. TNFR family contains several members and superfamily ('''TNFRSF''') members. <br /> | ||
* '''TNFRSF 1''' is called '''Lymphotoxin-α or TNF-β''';<br /> | * '''TNFRSF 1''' is called '''Lymphotoxin-α or TNF-β'''<ref>PMID:20566898</ref>;<br /> | ||
* '''TNFRSF 3''' is called '''TNFR-III''';<br /> | * '''TNFRSF 3''' is called '''TNFR-III''';<br /> | ||
* '''TNFRSF 4''' is called '''OX40L receptor''';<br /> | * '''TNFRSF 4''' is called '''OX40L receptor''';<br /> | ||
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* '''TNFRSF 25''' is called '''Dr3''';<br /> | * '''TNFRSF 25''' is called '''Dr3''';<br /> | ||
See also [[Tumor necrosis factor ligand superfamily]] | See also | ||
*[[Tumor necrosis factor ligand superfamily]] | |||
*[[Cytokine receptors]] | |||
*[[Receptor]] | |||
*[[Immune receptors]] | |||
== Relevance == | == Relevance == | ||
TRAPS - a condition characterized by recurrent episodes of fever is associated with TNFR<ref>PMID:24609716</ref>. | TRAPS - a condition characterized by recurrent episodes of fever is associated with TNFR<ref>PMID:24609716</ref>. | ||