4onv: Difference between revisions

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-'''Unreleased structure'''
-The entry 4onv is ON HOLD
+==Crystal structure of YagE, a KDG aldolase protein in complex with 2-Keto-3-deoxy gluconate==
+<StructureSection load='4onv' size='340' side='right'caption='[[4onv]], [[Resolution|resolution]] 2.57&Aring;' scene=''>
-Authors: Kumar, M., Bhaskar, V., Manicka, S., Krishnaswamy, S.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4onv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ONV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ONV FirstGlance]. <br>
-Description: Crystal Structure of YagE in complex with 2-keto-3-deoxy gluconate, pyruvate and glyceraldehyde
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.57&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KDG:2-KETO-3-DEOXYGLUCONATE'>KDG</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4onv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4onv OCA], [https://pdbe.org/4onv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4onv RCSB], [https://www.ebi.ac.uk/pdbsum/4onv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4onv ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/YAGE_ECOLI YAGE_ECOLI] Catalyzes the formation of 2-keto-3-deoxy-galactonate (KDGal) from pyruvate and glyceraldehyde. Overexpression leads to increased growth (over 2 hours) in the presence of the antibiotics norfloxacin, ampicillin and streptomycin.
+__TOC__
+</StructureSection>
+[[Category: Escherichia coli K-12]]
+[[Category: Large Structures]]
+[[Category: Bhaskar V]]
+[[Category: Krishnaswamy S]]
+[[Category: Manicka S]]
+[[Category: Manoj Kumar P]]