4o9r: Difference between revisions

<StructureSection load='4o9r' size='340' side='right' caption='[[4o9r]], [[Resolution|resolution]] 3.20&Aring;' scene=''>

<table><tr><td colspan='2'>[[4o9r]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O9R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4O9R FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CY8:CYCLOPAMINE'>CY8</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o9r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o9r OCA], [http://pdbe.org/4o9r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4o9r RCSB], [http://www.ebi.ac.uk/pdbsum/4o9r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4o9r ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/SMO_HUMAN SMO_HUMAN]] G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.<ref>PMID:19592253</ref>

[[Category: Bacillus coli migula 1895]]

[[Category: Barty, A]]

[[Category: Basu, S]]

[[Category: Beyerlein, K R]]

[[Category: Boutet, S]]

[[Category: Caffrey, M]]

[[Category: Chapman, H N]]

[[Category: Cherezov, V]]

[[Category: Doak, R B]]

[[Category: Fromme, P]]

[[Category: Fromme, R]]

[[Category: GPCR, GPCR Network]]

[[Category: Gati, C]]

[[Category: Grotjohann, I]]

[[Category: Han, G W]]

[[Category: Howe, N]]

[[Category: James, D]]

[[Category: Katritch, V]]

[[Category: Kirian, R A]]

[[Category: Klinker, M]]

[[Category: Koglin, J E]]

[[Category: Kupitz, C]]

[[Category: Li, D]]

[[Category: Liu, H]]

[[Category: Liu, W]]

[[Category: Messerschmidt, M]]

[[Category: Nelson, G]]

[[Category: Seibert, M M]]

[[Category: Shah, S T.A]]

[[Category: Shoeman, R L]]

[[Category: Spence, J C.H]]

[[Category: Stevens, R C]]

[[Category: Wacker, D]]

[[Category: Wang, C]]

[[Category: Wang, D]]

[[Category: Weierstall, U]]

[[Category: White, T A]]

[[Category: Willams, G J]]

[[Category: Zatsepin, N A]]

[[Category: Xfel]]