4ntm: Difference between revisions

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==QueD soaked with sepiapterin (selenomethionine substituted protein)==
==QueD soaked with sepiapterin (selenomethionine substituted protein)==
<StructureSection load='4ntm' size='340' side='right' caption='[[4ntm]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='4ntm' size='340' side='right'caption='[[4ntm]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ntm]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NTM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NTM FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ntm]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NTM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NTM FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2K8:(6R)-2-AMINO-4-OXO-3,4,5,6,7,8-HEXAHYDROPTERIDINE-6-CARBOXYLIC+ACID'>2K8</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2K8:(6R)-2-AMINO-4-OXO-3,4,5,6,7,8-HEXAHYDROPTERIDINE-6-CARBOXYLIC+ACID'>2K8</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ntk|4ntk]], [[4ntn|4ntn]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ntm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ntm OCA], [https://pdbe.org/4ntm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ntm RCSB], [https://www.ebi.ac.uk/pdbsum/4ntm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ntm ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/6-carboxytetrahydropterin_synthase 6-carboxytetrahydropterin synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.50 4.1.2.50] </span></td></tr>
</table>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ntm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ntm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ntm RCSB], [http://www.ebi.ac.uk/pdbsum/4ntm PDBsum]</span></td></tr>
== Function ==
<table>
[https://www.uniprot.org/uniprot/QUED_ECOLI QUED_ECOLI] Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde. Can also convert 6-pyruvoyltetrahydropterin (PPH4) and sepiapterin to CPH4; these 2 compounds are probably intermediates in the reaction from H2NTP.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4ntm" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: 6-carboxytetrahydropterin synthase]]
[[Category: Escherichia coli K-12]]
[[Category: Bandarian, V.]]
[[Category: Large Structures]]
[[Category: Miles, Z D.]]
[[Category: Bandarian V]]
[[Category: S A., Roberts.]]
[[Category: Miles ZD]]
[[Category: 6-ptp]]
[[Category: Roberts SA]]
[[Category: Lyase]]
[[Category: Queuosine biosynthesis enzyme]]
[[Category: Sepiapterin]]
[[Category: T-fold]]

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