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==2.4 Angstrom Resolution Crystal Structure of Putative Sugar Kinase from Campylobacter jejuni.==
==2.4 Angstrom Resolution Crystal Structure of Putative Sugar Kinase from Campylobacter jejuni.==
<StructureSection load='4n3o' size='340' side='right' caption='[[4n3o]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='4n3o' size='340' side='right'caption='[[4n3o]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4n3o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Camje Camje]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N3O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4N3O FirstGlance]. <br>
<table><tr><td colspan='2'>[[4n3o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Campylobacter_jejuni_subsp._jejuni_NCTC_11168_=_ATCC_700819 Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N3O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N3O FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hddA, Cj1425c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=192222 CAMJE])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n3o OCA], [https://pdbe.org/4n3o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n3o RCSB], [https://www.ebi.ac.uk/pdbsum/4n3o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n3o ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4n3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n3o OCA], [http://pdbe.org/4n3o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4n3o RCSB], [http://www.ebi.ac.uk/pdbsum/4n3o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4n3o ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HDDA_CAMJE HDDA_CAMJE] Catalyzes the phosphorylation of D-glycero-alpha-D-manno-heptose 7-phosphate at the C-1 position to form D-glycero-alpha-D-manno-heptose 1,7-bisphosphate.<ref>PMID:31449400</ref>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Camje]]
[[Category: Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]]
[[Category: Anderson, W F]]
[[Category: Large Structures]]
[[Category: Structural genomic]]
[[Category: Anderson WF]]
[[Category: Gordon, E]]
[[Category: Gordon E]]
[[Category: Grimshaw, S]]
[[Category: Grimshaw S]]
[[Category: Kwon, K]]
[[Category: Kwon K]]
[[Category: Minasov, G]]
[[Category: Minasov G]]
[[Category: Onopriyenko, O]]
[[Category: Onopriyenko O]]
[[Category: Savchenko, A]]
[[Category: Savchenko A]]
[[Category: Wawrzak, Z]]
[[Category: Wawrzak Z]]
[[Category: Csgid]]
[[Category: National institute of allergy and infectious disease]]
[[Category: Niaid]]
[[Category: Transferase]]

Latest revision as of 13:18, 30 October 2024

2.4 Angstrom Resolution Crystal Structure of Putative Sugar Kinase from Campylobacter jejuni.2.4 Angstrom Resolution Crystal Structure of Putative Sugar Kinase from Campylobacter jejuni.

Structural highlights

4n3o is a 2 chain structure with sequence from Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.4Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HDDA_CAMJE Catalyzes the phosphorylation of D-glycero-alpha-D-manno-heptose 7-phosphate at the C-1 position to form D-glycero-alpha-D-manno-heptose 1,7-bisphosphate.[1]

References

  1. ↑ Huddleston JP, Raushel FM. Biosynthesis of GDP-d-glycero-alpha-d-manno-heptose for the Capsular Polysaccharide of Campylobacter jejuni. Biochemistry. 2019 Sep 17;58(37):3893-3902. doi: 10.1021/acs.biochem.9b00548. , Epub 2019 Aug 29. PMID:31449400 doi:http://dx.doi.org/10.1021/acs.biochem.9b00548

4n3o, resolution 2.40Å

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