4c85: Difference between revisions

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==zebrafish ZNRF3 ectodomain crystal form II==
==zebrafish ZNRF3 ectodomain crystal form II==
<StructureSection load='4c85' size='340' side='right' caption='[[4c85]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='4c85' size='340' side='right'caption='[[4c85]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4c85]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Brachidanio_rerio Brachidanio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C85 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4C85 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4c85]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Danio_rerio Danio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C85 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C85 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4c84|4c84]], [[4c86|4c86]], [[4c8a|4c8a]], [[4c8c|4c8c]], [[4c8f|4c8f]], [[4c8p|4c8p]], [[4c8t|4c8t]], [[4c8u|4c8u]], [[4c8v|4c8v]], [[4c8w|4c8w]], [[4c99|4c99]], [[4c9a|4c9a]], [[4c9e|4c9e]], [[4c9r|4c9r]], [[4c9u|4c9u]], [[4c9v|4c9v]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c85 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c85 OCA], [http://pdbe.org/4c85 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4c85 RCSB], [http://www.ebi.ac.uk/pdbsum/4c85 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4c85 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c85 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c85 OCA], [https://pdbe.org/4c85 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c85 RCSB], [https://www.ebi.ac.uk/pdbsum/4c85 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c85 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ZNRF3_DANRE ZNRF3_DANRE]] E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components.  
[https://www.uniprot.org/uniprot/ZNRF3_DANRE ZNRF3_DANRE] E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Ubiquitin protein ligase|Ubiquitin protein ligase]]
*[[Ubiquitin protein ligase 3D structures|Ubiquitin protein ligase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Brachidanio rerio]]
[[Category: Danio rerio]]
[[Category: Jones, E Y]]
[[Category: Large Structures]]
[[Category: Zebisch, M]]
[[Category: Jones EY]]
[[Category: Lgr4]]
[[Category: Zebisch M]]
[[Category: Lgr5]]
[[Category: Lgr6]]
[[Category: Ligase]]
[[Category: Membrane]]
[[Category: R-spo]]
[[Category: R-spondin]]
[[Category: Receptor]]
[[Category: Rnf43]]
[[Category: Rspo]]
[[Category: Rspo1]]
[[Category: Rspo2]]
[[Category: Rspo3]]
[[Category: Rspo4]]
[[Category: Signalling]]
[[Category: Wnt]]

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