4lrt: Difference between revisions

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-'''Unreleased structure'''
-The entry 4lrt is ON HOLD
+==Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site==
+<StructureSection load='4lrt' size='340' side='right'caption='[[4lrt]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4lrt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermomonospora_curvata_DSM_43183 Thermomonospora curvata DSM 43183]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LRT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LRT FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lrt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lrt OCA], [https://pdbe.org/4lrt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lrt RCSB], [https://www.ebi.ac.uk/pdbsum/4lrt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lrt ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/D1A3K7_THECD D1A3K7_THECD] Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity).[HAMAP-Rule:MF_01657]
-Authors: Fischer, B., Branlant, G., Talfournier, F., Gruez, A.
+==See Also==
+*[[Aldolase 3D structures|Aldolase 3D structures]]
-Description: Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Thermomonospora curvata DSM 43183]]
+[[Category: Branlant G]]
+[[Category: Fischer B]]
+[[Category: Gruez A]]
+[[Category: Talfournier F]]