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==Crystal structure of coactosin from Entamoeba histolytica==
==Crystal structure of coactosin from Entamoeba histolytica==
<StructureSection load='4liz' size='340' side='right' caption='[[4liz]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='4liz' size='340' side='right'caption='[[4liz]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4liz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Entamoeba_histolytica_hm-1:imss-a Entamoeba histolytica hm-1:imss-a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LIZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LIZ FirstGlance]. <br>
<table><tr><td colspan='2'>[[4liz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Entamoeba_histolytica_HM-1:IMSS-A Entamoeba histolytica HM-1:IMSS-A]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LIZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LIZ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.499&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1t2l|1t2l]], [[1vfq|1vfq]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4liz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4liz OCA], [https://pdbe.org/4liz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4liz RCSB], [https://www.ebi.ac.uk/pdbsum/4liz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4liz ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Actin binding protein, Cofilin/tropomyosin family, EHI7A_006660 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=885318 Entamoeba histolytica HM-1:IMSS-A])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4liz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4liz OCA], [http://pdbe.org/4liz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4liz RCSB], [http://www.ebi.ac.uk/pdbsum/4liz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4liz ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/COAA_ENTH1 COAA_ENTH1] Actin-binding protein which is involved in F-actin stabilization (PubMed:25210743). May play a role during phagocytosis and pseudopod formation by contributing to the maintenance of F-actin (PubMed:25210743).<ref>PMID:25210743</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Entamoeba histolytica hm-1:imss-a]]
[[Category: Entamoeba histolytica HM-1:IMSS-A]]
[[Category: Gourinath, S]]
[[Category: Large Structures]]
[[Category: Kumar, N]]
[[Category: Gourinath S]]
[[Category: Actin]]
[[Category: Kumar N]]
[[Category: Actin binding protein]]
[[Category: Coactosin]]
[[Category: Structural protein]]

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