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==Crystal Structure of AmpC beta-lactamase N152G Mutant in Complex with Cefoxitin== | ==Crystal Structure of AmpC beta-lactamase N152G Mutant in Complex with Cefoxitin== | ||
<StructureSection load='4ken' size='340' side='right' caption='[[4ken]], [[Resolution|resolution]] 1.89Å' scene=''> | <StructureSection load='4ken' size='340' side='right'caption='[[4ken]], [[Resolution|resolution]] 1.89Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4ken]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KEN OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[4ken]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KEN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KEN FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1S7:(2R)-2-{(1S)-1-METHOXY-2-OXO-1-[(THIOPHEN-2-YLACETYL)AMINO]ETHYL}-5-METHYLIDENE-5,6-DIHYDRO-2H-1,3-THIAZINE-4-CARBOXYLIC+ACID'>1S7</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.89Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1S7:(2R)-2-{(1S)-1-METHOXY-2-OXO-1-[(THIOPHEN-2-YLACETYL)AMINO]ETHYL}-5-METHYLIDENE-5,6-DIHYDRO-2H-1,3-THIAZINE-4-CARBOXYLIC+ACID'>1S7</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ken FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ken OCA], [https://pdbe.org/4ken PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ken RCSB], [https://www.ebi.ac.uk/pdbsum/4ken PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ken ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/AMPC_ECOLI AMPC_ECOLI] This protein is a serine beta-lactamase with a substrate specificity for cephalosporins. | |||
==See Also== | |||
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Escherichia coli K-12]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Baggett VL]] | ||
[[Category: | [[Category: Docter BE]] | ||
[[Category: | [[Category: Powers RA]] | ||
[[Category: | [[Category: Wallar BJ]] | ||
Latest revision as of 14:03, 6 November 2024
Crystal Structure of AmpC beta-lactamase N152G Mutant in Complex with CefoxitinCrystal Structure of AmpC beta-lactamase N152G Mutant in Complex with Cefoxitin
Structural highlights
FunctionAMPC_ECOLI This protein is a serine beta-lactamase with a substrate specificity for cephalosporins. See Also |
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