Protein phosphatase: Difference between revisions
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== Function == | == Function == | ||
'''Protein phosphatases''' (PP) or '''serine/threonine protein phosphatase''' regulate protein phosphorylation and thus are key in intracellular signal transduction processes.<br /> | '''Protein phosphatases''' (PP) or '''serine/threonine protein phosphatase''' regulate protein phosphorylation and thus are key in intracellular signal transduction processes.<br /> | ||
* '''PP1''' is a serine/threonine phosphatase and is a key component of the insulin signaling pathway<ref>PMID:9609113</ref>.<br /> | * '''PP1''' is a serine/threonine phosphatase and is a key component of the insulin signaling pathway<ref>PMID:9609113</ref>.<br /> | ||
* ''' | * '''PP1C''' is the catalytic subunit of PP1. | ||
* '''PP1K''' is Mn+2/Mg+2-dependent PP1. | |||
* '''PP2A''' targets proteins in the oncogenic signaling pathways<ref>PMID:11812651</ref>. For PP2A see also [[HEAT Repeat]].<br /> | * '''PP2A''' targets proteins in the oncogenic signaling pathways<ref>PMID:11812651</ref>. For PP2A see also [[HEAT Repeat]].<br /> | ||
* '''PP2C''' are Mg/Mn-dependent and are essential for the regulation of cell cycle and stress signaling pathways. For details see<br /> | * '''PP2C''' are Mg/Mn-dependent and are essential for the regulation of cell cycle and stress signaling pathways. For details see<br /> | ||
* <scene name='54/540142/Protein_pp2cm_with_mgii/4'>PP2Cm</scene> | |||
*[[Protein Phosphatase 2C]]<br /> | *[[Protein Phosphatase 2C]]<br /> | ||
*[[ABA-regulated Protein Phosphatase 2C]]<br /> | *[[ABA-regulated Protein Phosphatase 2C]]<br /> | ||