3w3j: Difference between revisions

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 ==Crystal structure of human TLR8 in complex with CL097==
-<StructureSection load='3w3j' size='340' side='right' caption='[[3w3j]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
+<StructureSection load='3w3j' size='340' side='right'caption='[[3w3j]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3w3j]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W3J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3W3J FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3w3j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W3J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W3J FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=C09:2-(ETHOXYMETHYL)-1H-IMIDAZO[4,5-C]QUINOLIN-4-AMINE'>C09</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3w3g|3w3g]], [[3w3k|3w3k]], [[3w3l|3w3l]], [[3w3m|3w3m]], [[3w3n|3w3n]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=C09:2-(ETHOXYMETHYL)-1H-IMIDAZO[4,5-C]QUINOLIN-4-AMINE'>C09</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TLR8, UNQ249/PRO286 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w3j OCA], [https://pdbe.org/3w3j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w3j RCSB], [https://www.ebi.ac.uk/pdbsum/3w3j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w3j ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w3j OCA], [http://pdbe.org/3w3j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3w3j RCSB], [http://www.ebi.ac.uk/pdbsum/3w3j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3w3j ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/TLR8_HUMAN TLR8_HUMAN]] Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.<ref>PMID:17932028</ref>
+[https://www.uniprot.org/uniprot/TLR8_HUMAN TLR8_HUMAN] Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.<ref>PMID:17932028</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 22: / Line 21: @@
 ==See Also==
-*[[Toll-like Receptors|Toll-like Receptors]]
+*[[Toll-like Receptor 3D structures|Toll-like Receptor 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
-[[Category: Ohto, U]]
+[[Category: Large Structures]]
-[[Category: Shimizu, T]]
+[[Category: Ohto U]]
-[[Category: Tanji, H]]
+[[Category: Shimizu T]]
-[[Category: Cl097]]
+[[Category: Tanji H]]
-[[Category: Glycosylation]]
-[[Category: Immune system]]
-[[Category: Innate immunity]]
-[[Category: Leucine rich repeat]]
-[[Category: Receptor]]
-[[Category: Rna]]
-[[Category: Rna binding]]
-[[Category: Rna receptor]]
-[[Category: Rna recognition]]
-[[Category: Secreted]]
-[[Category: Ssrna]]