4h2b: Difference between revisions

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 ==Human ecto-5'-nucleotidase (CD73): crystal form II (open) in complex with Baicalin==
-<StructureSection load='4h2b' size='340' side='right' caption='[[4h2b]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
+<StructureSection load='4h2b' size='340' side='right'caption='[[4h2b]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4h2b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H2B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H2B FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4h2b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H2B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H2B FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0XE:5,6-DIHYDROXY-4-OXO-2-PHENYL-4H-CHROMEN-7-YL+BETA-D-GLUCOPYRANOSIDURONIC+ACID'>0XE</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4h1y|4h1y]], [[4h2f|4h2f]], [[4h2i|4h2i]], [[4h2g|4h2g]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0XE:5,6-DIHYDROXY-4-OXO-2-PHENYL-4H-CHROMEN-7-YL+BETA-D-GLUCOPYRANOSIDURONIC+ACID'>0XE</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NT5, NT5E, NTE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h2b OCA], [https://pdbe.org/4h2b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h2b RCSB], [https://www.ebi.ac.uk/pdbsum/4h2b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h2b ProSAT]</span></td></tr>
-<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5'-nucleotidase 5'-nucleotidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.5 3.1.3.5] </span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h2b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h2b RCSB], [http://www.ebi.ac.uk/pdbsum/4h2b PDBsum]</span></td></tr>
 </table>
 == Disease ==
-[[http://www.uniprot.org/uniprot/5NTD_HUMAN 5NTD_HUMAN]] Hereditary arterial and articular multiple calcification syndrome. The disease is caused by mutations affecting the gene represented in this entry.
+[https://www.uniprot.org/uniprot/5NTD_HUMAN 5NTD_HUMAN] Hereditary arterial and articular multiple calcification syndrome. The disease is caused by mutations affecting the gene represented in this entry.
 == Function ==
-[[http://www.uniprot.org/uniprot/5NTD_HUMAN 5NTD_HUMAN]] Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities.<ref>PMID:21933152</ref>
+[https://www.uniprot.org/uniprot/5NTD_HUMAN 5NTD_HUMAN] Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities.<ref>PMID:21933152</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
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 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 4h2b" style="background-color:#fffaf0;"></div>
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: 5'-nucleotidase]]
 [[Category: Homo sapiens]]
-[[Category: Knapp, K]]
+[[Category: Large Structures]]
-[[Category: Pippel, J]]
+[[Category: Knapp K]]
-[[Category: Straeter, N]]
+[[Category: Pippel J]]
-[[Category: Zebisch, M]]
+[[Category: Straeter N]]
-[[Category: Dimer]]
+[[Category: Zebisch M]]
-[[Category: Extracellular]]
-[[Category: Hydrolase phosphatase nucleotidase]]
-[[Category: Hydrolase-hydrolase inhibitor complex]]