4fom: Difference between revisions

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 ==Crystal structure of human nectin-3 full ectodomain (D1-D3)==
-<StructureSection load='4fom' size='340' side='right' caption='[[4fom]], [[Resolution|resolution]] 3.93&Aring;' scene=''>
+<StructureSection load='4fom' size='340' side='right'caption='[[4fom]], [[Resolution|resolution]] 3.93&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4fom]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FOM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FOM FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4fom]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FOM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FOM FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.93&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4fmf|4fmf]], [[4fmk|4fmk]], [[4fn0|4fn0]], [[4fqp|4fqp]], [[4frw|4frw]], [[4fs0|4fs0]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PVRL3, PRR3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fom FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fom OCA], [https://pdbe.org/4fom PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fom RCSB], [https://www.ebi.ac.uk/pdbsum/4fom PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fom ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fom FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fom OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fom RCSB], [http://www.ebi.ac.uk/pdbsum/4fom PDBsum]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/PVRL3_HUMAN PVRL3_HUMAN]] Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with PVRL2/nectin-2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.<ref>PMID:16216929</ref>
+[https://www.uniprot.org/uniprot/NECT3_HUMAN NECT3_HUMAN] Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.<ref>PMID:16216929</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 18: / Line 18: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 4fom" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Poliovirus receptor-related protein|Poliovirus receptor-related protein]]
 == References ==
 <references/>
@@ Line 23: / Line 27: @@
 </StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Brasch, J]]
+[[Category: Large Structures]]
-[[Category: Harrison, O J]]
+[[Category: Brasch J]]
-[[Category: Jin, X]]
+[[Category: Harrison OJ]]
-[[Category: Shapiro, L]]
+[[Category: Jin X]]
-[[Category: Cell adhesion]]
+[[Category: Shapiro L]]
-[[Category: Ig domain]]
-[[Category: Immunoglobulin-like domain]]