2gu2: Difference between revisions
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==Crystal Structure of an Aspartoacylase from Rattus norvegicus== | ==Crystal Structure of an Aspartoacylase from Rattus norvegicus== | ||
<StructureSection load='2gu2' size='340' side='right'caption='[[2gu2]], [[Resolution|resolution]] 1. | <StructureSection load='2gu2' size='340' side='right'caption='[[2gu2]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2gu2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2gu2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GU2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GU2 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.805Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gu2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gu2 OCA], [https://pdbe.org/2gu2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gu2 RCSB], [https://www.ebi.ac.uk/pdbsum/2gu2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gu2 ProSAT], [https://www.topsan.org/Proteins/CESG/2gu2 TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gu2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gu2 OCA], [https://pdbe.org/2gu2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gu2 RCSB], [https://www.ebi.ac.uk/pdbsum/2gu2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gu2 ProSAT], [https://www.topsan.org/Proteins/CESG/2gu2 TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/ACY2_RAT ACY2_RAT] Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter (By similarity). | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gu/2gu2_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gu/2gu2_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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==See Also== | ==See Also== | ||
*[[Aminoacylase 3D structures|Aminoacylase 3D structures]] | *[[Aminoacylase 3D structures|Aminoacylase 3D structures]] | ||
*[[Aspartoacylase 3D structures|Aspartoacylase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Rattus norvegicus]] | ||
[[Category: | [[Category: Bingman CA]] | ||
[[Category: | [[Category: Bitto E]] | ||
[[Category: Phillips | [[Category: Phillips Jr GN]] | ||
[[Category: Wesenberg | [[Category: Wesenberg GE]] | ||