2v9d: Difference between revisions

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==Crystal Structure of YagE, a prophage protein belonging to the dihydrodipicolinic acid synthase family from E. coli K12==
The line below this paragraph, containing "STRUCTURE_2v9d", creates the "Structure Box" on the page.
<StructureSection load='2v9d' size='340' side='right'caption='[[2v9d]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2v9d]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V9D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V9D FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
{{STRUCTURE_2v9d| PDB=2v9d |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v9d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v9d OCA], [https://pdbe.org/2v9d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v9d RCSB], [https://www.ebi.ac.uk/pdbsum/2v9d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v9d ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/YAGE_ECOLI YAGE_ECOLI] Catalyzes the formation of 2-keto-3-deoxy-galactonate (KDGal) from pyruvate and glyceraldehyde. Overexpression leads to increased growth (over 2 hours) in the presence of the antibiotics norfloxacin, ampicillin and streptomycin.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v9/2v9d_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2v9d ConSurf].
<div style="clear:both"></div>


===CRYSTAL STRUCTURE OF YAGE, A PROPHAGE PROTEIN BELONGING TO THE DIHYDRODIPICOLINIC ACID SYNTHASE FAMILY FROM E. COLI K12===
==See Also==
 
*[[Dihydrodipicolinate synthase|Dihydrodipicolinate synthase]]
 
__TOC__
==About this Structure==
</StructureSection>
[[2v9d]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V9D OCA].
[[Category: Escherichia coli K-12]]
 
[[Category: Large Structures]]
==Reference==
[[Category: Albeck S]]
<ref group="xtra">PMID:018361457</ref><references group="xtra"/>
[[Category: Bourenkov G]]
[[Category: Escherichia coli]]
[[Category: Dym O]]
[[Category: Albeck, S.]]
[[Category: Greenblatt HM]]
[[Category: Bourenkov, G.]]
[[Category: Krishnaswamy S]]
[[Category: Dym, O.]]
[[Category: Lamzin V]]
[[Category: Greenblatt, H M.]]
[[Category: Manicka S]]
[[Category: Krishnaswamy, S.]]
[[Category: Peleg Y]]
[[Category: Lamzin, V.]]
[[Category: Sussman JL]]
[[Category: Manicka, S.]]
[[Category: Unger T]]
[[Category: Peleg, Y.]]
[[Category: Sussman, J L.]]
[[Category: Unger, T.]]
[[Category: Dhdp]]
[[Category: Dihydrodipicolinic acid synthase]]
[[Category: Lyase]]
[[Category: N-acetyl neuraminate lyase]]
[[Category: Nal]]
[[Category: Prophage]]

Latest revision as of 04:26, 21 November 2024

Crystal Structure of YagE, a prophage protein belonging to the dihydrodipicolinic acid synthase family from E. coli K12Crystal Structure of YagE, a prophage protein belonging to the dihydrodipicolinic acid synthase family from E. coli K12

Structural highlights

2v9d is a 4 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.15Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

YAGE_ECOLI Catalyzes the formation of 2-keto-3-deoxy-galactonate (KDGal) from pyruvate and glyceraldehyde. Overexpression leads to increased growth (over 2 hours) in the presence of the antibiotics norfloxacin, ampicillin and streptomycin.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2v9d, resolution 2.15Å

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