2x97: Difference between revisions
No edit summary |
No edit summary |
||
| Line 3: | Line 3: | ||
<StructureSection load='2x97' size='340' side='right'caption='[[2x97]], [[Resolution|resolution]] 1.85Å' scene=''> | <StructureSection load='2x97' size='340' side='right'caption='[[2x97]], [[Resolution|resolution]] 1.85Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2x97]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2x97]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X97 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X97 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=RX4:N~2~-ACETYL-N-{(1R)-1-[(S)-[(2S)-3-{[(2S)-1-AMINO-1-OXOPROPAN-2-YL]AMINO}-2-METHYL-3-OXOPROPYL](HYDROXY)PHOSPHORYL]-2-PHENYLETHYL}-L-ALPHA-ASPARAGINE'>RX4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=RX4:N~2~-ACETYL-N-{(1R)-1-[(S)-[(2S)-3-{[(2S)-1-AMINO-1-OXOPROPAN-2-YL]AMINO}-2-METHYL-3-OXOPROPYL](HYDROXY)PHOSPHORYL]-2-PHENYLETHYL}-L-ALPHA-ASPARAGINE'>RX4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x97 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x97 OCA], [https://pdbe.org/2x97 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x97 RCSB], [https://www.ebi.ac.uk/pdbsum/2x97 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x97 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x97 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x97 OCA], [https://pdbe.org/2x97 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x97 RCSB], [https://www.ebi.ac.uk/pdbsum/2x97 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x97 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/ACE_DROME ACE_DROME] May be involved in the specific maturation or degradation of a number of bioactive peptides. May play a role in the contractions of the heart, gut and testes, and in spermatid differentiation.<ref>PMID:12591244</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 16: | Line 15: | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x9/2x97_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x9/2x97_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| Line 38: | Line 37: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Drosophila melanogaster]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Acharya KR]] | |||
[[Category: Acharya | [[Category: Akif M]] | ||
[[Category: Akif | [[Category: Dive V]] | ||
[[Category: Dive | [[Category: Georgiadis D]] | ||
[[Category: Georgiadis | [[Category: Isaac RE]] | ||
[[Category: Isaac | [[Category: Mahajan A]] | ||
[[Category: Mahajan | [[Category: Sturrock ED]] | ||
[[Category: Sturrock | |||