4dt3: Difference between revisions

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-{{STRUCTURE_4dt3|  PDB=4dt3  |  SCENE=  }}
-===Crystal structure of zinc-charged lysozyme===
-{{ABSTRACT_PUBMED_22948927}}
-==Function==
+==Crystal structure of zinc-charged lysozyme==
-[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
+<StructureSection load='4dt3' size='340' side='right'caption='[[4dt3]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4dt3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DT3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DT3 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dt3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dt3 OCA], [https://pdbe.org/4dt3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dt3 RCSB], [https://www.ebi.ac.uk/pdbsum/4dt3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dt3 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Zinc is a suitable metal for anomalous dispersion phasing methods in protein crystallography. Structure determination using zinc anomalous scattering has been almost exclusively limited to proteins with intrinsically bound zinc(s). Here, it is reported that multiple zinc ions can easily be charged onto the surface of proteins with no intrinsic zinc-binding site by using zinc-containing solutions. Zn derivatization of protein surfaces appears to be a largely unnoticed but promising method of protein structure determination.
-==About this Structure==
+Experimental phasing using zinc anomalous scattering.,Cha SS, An YJ, Jeong CS, Kim MK, Lee SG, Lee KH, Oh BH Acta Crystallogr D Biol Crystallogr. 2012 Sep;68(Pt 9):1253-8. doi:, 10.1107/S0907444912024420. Epub 2012 Aug 18. PMID:22948927<ref>PMID:22948927</ref>
-[[4dt3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DT3 OCA].
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
+<div class="pdbe-citations 4dt3" style="background-color:#fffaf0;"></div>
 ==See Also==
-*[[Hen Egg-White (HEW) Lysozyme|Hen Egg-White (HEW) Lysozyme]]
+*[[Lysozyme 3D structures|Lysozyme 3D structures]]
+== References ==
-==Reference==
+<references/>
-<ref group="xtra">PMID:022948927</ref><references group="xtra"/><references/>
+__TOC__
+</StructureSection>
 [[Category: Gallus gallus]]
-[[Category: Lysozyme]]
+[[Category: Large Structures]]
-[[Category: An, Y J.]]
+[[Category: An YJ]]
-[[Category: Cha, S S.]]
+[[Category: Cha SS]]
-[[Category: Jeong, C S.]]
+[[Category: Jeong CS]]
-[[Category: Hydrolase]]
-[[Category: Lysozyme]]