1v04: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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 ==serum paraoxonase by directed evolution==
-<StructureSection load='1v04' size='340' side='right' caption='[[1v04]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
+<StructureSection load='1v04' size='340' side='right'caption='[[1v04]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1v04]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V04 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V04 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1v04]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus], [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus] and [https://en.wikipedia.org/wiki/Rattus_rattus Rattus rattus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V04 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V04 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v04 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v04 OCA], [http://pdbe.org/1v04 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1v04 RCSB], [http://www.ebi.ac.uk/pdbsum/1v04 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1v04 ProSAT], [http://www.topsan.org/Proteins/ISPC/1v04 TOPSAN]</span></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v04 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v04 OCA], [https://pdbe.org/1v04 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v04 RCSB], [https://www.ebi.ac.uk/pdbsum/1v04 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v04 ProSAT], [https://www.topsan.org/Proteins/ISPC/1v04 TOPSAN]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/PON1_RABIT PON1_RABIT] Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification.<ref>PMID:11266077</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 12: / Line 15: @@
    <jmolCheckbox>
      <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v0/1v04_consurf.spt"</scriptWhenChecked>
-     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
    </jmolCheckbox>
@@ Line 28: / Line 31: @@
 ==See Also==
-*[[Joel Sussman's Favorites|Joel Sussman's Favorites]]
 *[[Serum Paraoxonase|Serum Paraoxonase]]
-*[[User:Boris Brumshtein|User:Boris Brumshtein]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
-[[Category: Aharoni, A]]
+[[Category: Large Structures]]
-[[Category: Brumshtein, B]]
+[[Category: Mus musculus]]
-[[Category: Dvir, H]]
+[[Category: Oryctolagus cuniculus]]
-[[Category: Gaidukov, L]]
+[[Category: Rattus rattus]]
-[[Category: Harel, M]]
+[[Category: Aharoni A]]
-[[Category: Khersonsky, O]]
+[[Category: Brumshtein B]]
-[[Category: McCarthy, A]]
+[[Category: Dvir H]]
-[[Category: Meged, R]]
+[[Category: Gaidukov L]]
-[[Category: Ravelli, R B.G]]
+[[Category: Harel M]]
-[[Category: Silman, I]]
+[[Category: Khersonsky O]]
-[[Category: Sussman, J L]]
+[[Category: McCarthy A]]
-[[Category: Tawfik, D S]]
+[[Category: Meged R]]
-[[Category: Toker, L]]
+[[Category: Ravelli RBG]]
-[[Category: Yagur, S]]
+[[Category: Silman I]]
-[[Category: Antioxidant]]
+[[Category: Sussman JL]]
-[[Category: Directed evolution]]
+[[Category: Tawfik DS]]
-[[Category: Hydrolase]]
+[[Category: Toker L]]
-[[Category: ISPC, Israel Structural Proteomics Center]]
+[[Category: Yagur S]]
-[[Category: Paraoxonase]]
-[[Category: Structural genomic]]