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| '''Chemotaxis proteins''' direct cell movement according to certain chemicals in their environment.<ref>PMID:4598187</ref> | | '''Chemotaxis proteins''' direct cell movement according to certain chemicals in their environment.<ref>PMID:4598187</ref> |
| For details on '''chemotaxis protein''' see<br />
| | *'''CheY''' is a response regulator determining the swimming behaviour of the cell<ref>PMID:7623663</ref>. |
| *[[Molecular Playground/Bacterial Chemotaxis Receptors]] for '''CheW'''<br /> | | *'''CheR''' is a SAM-dependent methyltransferase which binds to the C-terminus of some chemotaxis receptors and methylates neighbouring receptor molecules<ref>PMID:9628482</ref>. See [[Molecular Playground/CheR]] and [[Chemotaxis receptor methyltransferase]]. |
| *[[Molecular Playground/Bacterial Chemotaxis Complex]] for '''CheA''' and '''CheW'''<br />
| | *'''CheA''' is a histidine kinase which donates phosphoric groups to CheB and CheY to control swimming behaviour<ref>PMID:15090507</ref>. See [[Molecular Playground/CheA]]. |
| *[[DNA Origami Assembly for the Tar Chemoreceptor]] for '''CheA''' and '''CheW'''<br />
| | *'''CheB''' is a methyltransferase catalysing the demethylationof chemotaxis membrane receptors in ''Salmonella typhimurium''<ref>PMID:2991277</ref>. |
| *[[Molecular Playground/CheA]] for '''CheA'''<br /> | | *'''CheW''' participates in the control of CheA activity<ref>PMID:1992467</ref>. See [[Molecular Playground/Bacterial Chemotaxis Receptors]] |
| *[[Molecular Playground/CheR]] and [[Chemotaxis receptor methyltransferase]] for chemotaxis receptor methyltransferase '''CheR''' .<ref>PMID:9628482</ref>
| | *'''PomA''' and '''PomB''' convert Na+ flux through channel to rotation of the flagellum in several bacteria <ref>PMID:21642461</ref>. |
| *[[Molecular Playground/cytoplasmic domain of a serine chemotaxis receptor]] for methyl-accepting chemotaxis protein.<br />
| | *'''Aspartate chemotaxis receptor''' or '''Tar''' modulates the activity of CheA<ref>PMID:8832891</ref>. See [[DNA Origami Assembly for the Tar Chemoreceptor]]. |
| *[[Molecular Playground/Cytoplasmic domain of chemoreceptor of Thermotoga maritima]]<br /> | | *'''Methyl-accepting chemotaxis protein''' are the predominant chemoreceptors in bacteria and archaea. They are involved in regulation of diverse aspects of cellular activities<ref>PMID:28409190</ref>. See [[Molecular Playground/cytoplasmic domain of a serine chemotaxis receptor]]. |
| *[[Receiver domain of sensor histidine kinase CKI1]].
| | *'''FLiN''', '''MotA''' and '''MotB''' are involved in energizing flagellar rotation in ''E. coli''<ref>PMID:7892209</ref>. |
| </StructureSection>
| | *'''CKI1''' is a histidine kinase involved in cytokinin signal transduction<ref>PMID:8875940</ref>. See [[Receiver domain of sensor histidine kinase CKI1]]. |
| ==3D structures of chemotaxis protein ==
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| Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
| | See also: |
| {{#tree:id=OrganizedByTopic|openlevels=0|
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| *CheY | | *[[Molecular Playground/Cytoplasmic domain of chemoreceptor of Thermotoga maritima]]<br /> |
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| **[[1ab6]], [[1d4z]], [[1e6m]], [[1e6k]], [[1e6l]], [[1jbe]], [[1mih]], [[3oo0]], [[3oo1]], [[6chy]], [[5chy]] – EcCheY (mutant) – ''Escherichia coli''<BR />
| | ==3D structures of chemotaxis protein == |
| **[[1tmy]], [[2tmy]], [[3tmy]], [[4tmy]] - TmCheY – ''Thermotoga maritima''<br />
| | [[Chemotaxis protein 3D structures]] |
| **[[4qyw]] - TmCheY (mutant) <br />
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| **[[4h60]], [[4hnr]], [[4jp1]] – VcCheY – ''Vibrio cholerae''<br />
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| **[[4hnq]] - VcCheY (mutant) <br />
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| **[[3gwg]] – HpCheY - ''Helicobacter pylori''<BR />
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| **[[3h1f]], [[3h1g]] - HpCheY (mutant) <BR />
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| **[[2id7]], [[2id9]], [[2idm]] – EcCheY-phosphono (mutant) <BR />
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| **[[1djm]] – EcCheY – NMR<BR />
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| **[[2chy]] – StCheY - ''Salmonella typhimurium'' <br />
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| **[[5hm6]] – CheY – ''Acinetobacter baumannii'' <br />
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| *''CheY complexes''
| | </StructureSection> |
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| **[[1zdm]] – EcCheY + Xe<BR />
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| **[[3h1e]] - HpCheY + BeF3 + Mn<BR />
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| **[[3f7n]], [[3fft]], [[3ffw]], [[3ffx]], [[3fgz]], [[3myy]], [[3olv]], [[3olw]], [[3olx]], [[3oly]] - EcCheY (mutant) + BeF3 + Mn<BR />
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| **[[4hns]] - VcCheY + BeF3 + Mg<br />
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| **[[4lx8]] - VcCheY + Mg<br />
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| **[[6ekg]] – CheY + Mg – ''Methaococcus maripaludis''<br />
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| **[[1fqw]] - EcCheY + BeF3 + Mn<br />
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| **[[3rvj]], [[3rvk]], [[3rvl]], [[3rvm]], [[3rvn]], [[3rvo]], [[3rvp]], [[3rvq]], [[3rvr]], [[3rvs]] - EcCheY (mutant) + BeF3 + Mn<br />
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| **[[5d2c]], [[5dgc]], [[5dkf]] - EcCheY (mutant) + BeF3 + Mn + imidazole<br />
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| **[[1bdj]] – EcCheY + aerobic respiration control protein HPT domain<BR />
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| **[[1u8t]] – EcCheY + flagellar motor switch protein FLIM<BR />
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| **[[2b1j]], [[1f4v]] - EcCheY + flagellar motor switch protein FLIM N terminal<br />
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| **[[1ffg]], [[1ffs]] – EcCheY + CheA CheY-binding domain<BR />
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| **[[1u0s]] - TmCheY response regulating domain + CheA P2 domain <BR />
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| **[[1ffw]] – EcCheY + CheA CheY-binding domain + imido phosphate<BR />
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| **[[1kmi]] - EcCheY + CheZ<BR />
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| **[[2lp4]] - EcCheY + CheA<br />
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| **[[2fka]], [[2flk]], [[2flw]], [[2fmf]], [[2fmh]], [[2fmi]], [[2fmk]], [[2pl9]], [[2pmc]] – StCheY + CheZ peptide <BR />
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| **[[2che]], [[2chf]] – StCheY + Mg<br />
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| **[[4iga]] - TmCheY + flagellar motor switch protein FLIM peptide<br />
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| *Chey-like
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| **[[3snk]] - CheyL - ''Mesorhizobium loti''<br />
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| **[[3cg4]], [[3crn]] - CheyL reciever domain - ''Methanospirillum hungatei''<br />
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| **[[3i42]] - CheyL receiver domain - ''Methylobacter flagellates''<br />
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| **[[3bre]] - CheyL - ''Pseudomonas aeruginosa''<br />
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| *CheX
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| **[[1xko]]– TmCheX<BR />
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| **[[3hm4]] – CheX – ''Desulfovibrio desulfuricans''<BR />
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| **[[3hzh]] – CheX + Che-3 – ''Borrelia burgdorferi''<br />
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| *CheC
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| **[[1xkr]] – TmCheC<BR />
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| **[[2f9z]] – TmCheC + CheD<BR />
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| **[[3qta]] – CheC – ''Haloarcula marismortui''<BR />
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| *CheR or chemotaxis protein methyltransferase
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| **[[1bc5]] – StCheR + chemotaxis receptor peptide <BR />
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| **[[1af7]] – StCheR<br />
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| **[[5ftw]] – CheR + SAH – ''Bacillus subtilis''<br />
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| *CheA
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| **[[1fwp]] – EcCheA – NMR<br />
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| **[[1b3q]] – TmCheA dimerization, kinase and regulatory domains <BR />
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| **[[1i5n]] – StCheA P1 domain<br />
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| **[[1i58]], [[1i59]], [[1i5a]], [[1i5b]], [[1i5d]] - TmCheA P4 domain + ATP analog<br />
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| **[[1i5c]] - TmCheA P4 domain (mutant) + ADP<br />
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| **[[1tqg]] – TmCheA phosphotransferase domain<br />
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| **[[2ld6]] – TmCheA HPT domain - NMR<BR />
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| **[[2ch4]] - TmCheA kinase and regulatory domains + CheW<br />
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| **[[4xiv]] - TmCheA kinase and dimerization domains<br />
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| **[[3ur1]], [[4jpb]] – TmCheA + CheW + methyl-accepting Che<br />
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| *CheB
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| **[[1a2o]], [[1chd]]– StCheB<br />
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| **[[3sft]] – TmCheB catalytic domain <br />
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| **[[3t8y]] – TmCheB response regulator domain<br />
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| *CheW
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| **[[1k0s]] – TmCheW<br />
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| **[[2ho9]] – EcCheW - NMR<BR />
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| *Aspartate chemotaxis receptor
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| **[[1jmw]], [[1vls]] – StChe LBD<br />
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| **[[1lih]] – StChe LBD (mutant)<br />
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| **[[1was]] – StChe LBD<br />
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| **[[1wat]], [[1vlt]], [[2lig]] – StChe LBD + aspartate<br />
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| **[[2asr]] – EcChe <br />
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| *Methyl-accepting chemotaxis protein
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| **[[2m7u]], [[2m7v]] – TeMche – ''Thermosynechococcus elongatus''<br />
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| **[[3vv4]] – TeMche GAF domain<br />
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| **[[4fof]], [[4glq]] – TeMche GAF domain (mutant)<br />
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| **[[3w2z]] – Mche residues 221-397 – Nostoc<br />
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| **[[3g67]] – TmMche<BR />
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| **[[3g6b]] – TmMche (mutant) <BR />
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| **[[2ch7]] – TmMche cytoplasmic domain<BR />
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| **[[1qu7]] – EcMcheI cytoplasmic domain<BR />
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| **[[2ld6]] – EcMche peptide - NMR<BR />
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| **[[4z9j]] - EcMcheII LBD <br />
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| **[[2d4u]] – EcMcheI LBD (mutant)<br />
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| **[[3zx6]] – EcMcheI/HAMP<br />
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| **[[1jmw]] - StMche LBD (mutant) <BR />
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| **[[2qhk]], [[4exo]] – Mche N-terminal – ''Vibrio parahaemolyticus''<BR />
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| **[[3c8c]] – Mche N-terminal <BR />
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| **[[3b47]] – Mche periplasmic domain – ''Geobacter sulfurreducens''<BR />
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| *Methyl-accepting chemotaxis protein complex
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| **[[3atp]] - EcMcheI LBD + serine<BR />
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| **[[4z9h]], [[4z9i]] - EcMcheII LBD + aspartic acid<br />
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| **[[5ave]] - VcMche LBD + serine<br />
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| **[[5avf]] - VcMche LBD + taurine<br />
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| **[[5t7m]], [[5t65]], [[5ltx]], [[5lto]], [[5lt9]] - PaMche LBD + amino acid – ''Pseudomonas aeruginosa''<br />
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| **[[5ltv]] - PaMche LBD + GABA<br />
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| **[[6f9g]] - Mche LBD + putrescine – ''Pseudomonas putida''<br />
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| *''Heme-containing methyl-accepting chemotaxis protein''
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| **[[3eee]], [[3iqb]], [[3lah]], [[3lai]], [[3sj5]], [[4fdk]] – TtMche H-Nox domain (mutant)<br />
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| **[[1xbn]] – TtMche – ''Thermoanaerobacter tengcongensis''<br />
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| **[[1u4h]], [[1u55]], [[1u56]], [[3tf0]], [[3tf1]] - TtMche H-Nox domain<br />
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| **[[3m0b]] - TtMche H-Nox domain Ru-porphyrin<br />
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| **[[3nvr]], [[3nvu]] – TtMche N terminal (mutant)<br />
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| **[[4it2]] - CsMche H-Nox domain Mn-porphyrin – ''Caldanaerobacter subterraneus''<br />
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| **[[5jru]] - CsMche H-Nox domain Fe-porphyrin <br />
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| **[[5jrv]] - CsMche H-Nox domain Fe-porphyrin + NO<br />
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| **[[5jrx]] - CsMche H-Nox domain Fe-porphyrin (mutant) + CO<br />
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| *Flagellar motor protein FLIN
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| **[[1yab]] – TmFLIN<BR />
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| *Chemotaxis protein MotB
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| **[[3cyp]], [[3imp]], [[3s02]], [[3s03]], [[3s06]], [[3s0h]], [[3s0w]], [[3s0y]] – HpMotB C terminal<br />
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| **[[3cyq]] – HpMotB C terminal + N-acetylmuramic acid<BR />
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| **[[2zov]], [[2zvy]], [[2zvz]] - StMotB C terminal<br />
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| *Chemotaxis protein CKI
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| **[[3mm4]] – AtCKI receiver domain – ''Arabidopsis thaliana''<br />
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| **[[3mmn]] – AtCKI receiver domain + Mg<br />
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| }}
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| == References == | | == References == |
| <references/> | | <references/> |
| [[Category:Topic Page]] | | [[Category:Topic Page]] |