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| {{STRUCTURE_1e6m PDB=1e6m | SIZE=400| SCENE= |right|CAPTION=E. coli CheY [[1e6m]] }}
| | <StructureSection load='1e6m' size='350' side='right' caption='E. coli CheY (PDB entry [[1e6m]])' scene=''> |
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| | '''Chemotaxis proteins''' direct cell movement according to certain chemicals in their environment.<ref>PMID:4598187</ref> |
| | *'''CheY''' is a response regulator determining the swimming behaviour of the cell<ref>PMID:7623663</ref>. |
| | *'''CheR''' is a SAM-dependent methyltransferase which binds to the C-terminus of some chemotaxis receptors and methylates neighbouring receptor molecules<ref>PMID:9628482</ref>. See [[Molecular Playground/CheR]] and [[Chemotaxis receptor methyltransferase]]. |
| | *'''CheA''' is a histidine kinase which donates phosphoric groups to CheB and CheY to control swimming behaviour<ref>PMID:15090507</ref>. See [[Molecular Playground/CheA]]. |
| | *'''CheB''' is a methyltransferase catalysing the demethylationof chemotaxis membrane receptors in ''Salmonella typhimurium''<ref>PMID:2991277</ref>. |
| | *'''CheW''' participates in the control of CheA activity<ref>PMID:1992467</ref>. See [[Molecular Playground/Bacterial Chemotaxis Receptors]] |
| | *'''PomA''' and '''PomB''' convert Na+ flux through channel to rotation of the flagellum in several bacteria <ref>PMID:21642461</ref>. |
| | *'''Aspartate chemotaxis receptor''' or '''Tar''' modulates the activity of CheA<ref>PMID:8832891</ref>. See [[DNA Origami Assembly for the Tar Chemoreceptor]]. |
| | *'''Methyl-accepting chemotaxis protein''' are the predominant chemoreceptors in bacteria and archaea. They are involved in regulation of diverse aspects of cellular activities<ref>PMID:28409190</ref>. See [[Molecular Playground/cytoplasmic domain of a serine chemotaxis receptor]]. |
| | *'''FLiN''', '''MotA''' and '''MotB''' are involved in energizing flagellar rotation in ''E. coli''<ref>PMID:7892209</ref>. |
| | *'''CKI1''' is a histidine kinase involved in cytokinin signal transduction<ref>PMID:8875940</ref>. See [[Receiver domain of sensor histidine kinase CKI1]]. |
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| | See also: |
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| For details on '''chemotaxis protein''' see<br />
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| *[[Molecular Playground/Bacterial Chemotaxis Receptors]]<br />
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| *[[Molecular Playground/Cytoplasmic domain of chemoreceptor of Thermotoga maritima]]<br /> | | *[[Molecular Playground/Cytoplasmic domain of chemoreceptor of Thermotoga maritima]]<br /> |
| *[[Receiver domain of sensor histidine kinase CKI1]].
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| ==3D structures of chemotaxis protein == | | ==3D structures of chemotaxis protein == |
| | [[Chemotaxis protein 3D structures]] |
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| | </StructureSection> |
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| ===CheY=== | | == References == |
| [[1ab6]], [[1d4z]], [[1e6m]], [[1e6k]], [[1e6l]], [[1jbe]], [[1mih]], [[3oo0]], [[3oo1]] – EcCheY (mutant) – ''Escherichia coli''<BR />
| | <references/> |
| [[3f7n]], [[3fft]], [[3ffw]], [[3ffx]], [[3fgz]], [[3myy]], [[3olv]], [[3olw]], [[3olx]], [[3oly]] - EcCheY (mutant) + BeF3 + Mn<BR />
| | [[Category:Topic Page]] |
| [[2id7]], [[2id9]], [[2idm]] – EcCheY-phosphono (mutant) <BR />
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| [[1djm]] – EcCheY – NMR<BR />
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| [[1zdm]] – EcCheY + Xe<BR />
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| [[3gwg]] – HpCheY - ''Helicobacter pylori''<BR />
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| [[3h1f]], [[3h1g]] - HpCheY (mutant) <BR />
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| [[3h1e]] - HpCheY + BeF3 + Mn<BR />
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| [[1bdj]] – EcCheY + aerobic respiration control protein HPT domain<BR />
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| [[1u8t]] – EcCheY + flagellar motor switch protein FLIM<BR />
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| [[2b1j]] - EcCheY + flagellar motor switch protein FLIM N terminal<br />
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| [[1ffg]], [[1ffs]] – EcCheY + CheA CheY-binding domain<BR />
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| [[1u0s]] - TmCheY response regulating domain + CheA P2 domain –''Thermotoga maritima''<BR />
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| [[1ffw]] – EcCheY + CheA CheY-binding domain + imido phosphate<BR />
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| [[1kmi]] - EcCheY + CheZ<BR />
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| [[2fka]], [[2flk]], [[2flw]], [[2fmf]], [[2fmh]], [[2fmi]], [[2fmk]], [[2pl9]], [[2pmc]] – StCheY + CheZ peptide - ''Salmonella typhimurium''<BR />
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| ===CheX===
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| [[1xko]]– TmCheX<BR />
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| [[3hm4]] – CheX – ''Desulfovibrio desulfuricans''<BR />
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| ===CheC===
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| [[1xkr]] – TmCheC<BR />
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| [[2f9z]] – TmCheC + CheD<BR />
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| [[3qta]] – CheC – ''Haloarcula marismortui''<BR />
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| ===CheR===
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| [[1bc5]] – StCheR + chemotaxis receptor peptide <BR />
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| ===CheA===
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| [[1b3q]] – TmCheA dimerization, kinase and regulatory domains <BR />
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| [[1i5n]] – StCheA P1 domain<br />
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| [[1i58]], [[1i59]], [[1i5a]], [[1i5b]], [[1i5d]] - TmCheA P4 domain + ATP analog<br />
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| [[1i5c]] - TmCheA P4 domain (mutant) + ADP<br />
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| [[1tqg]] – TmCheA phosphotransferase domain<br /> | |
| [[2ld6]] – TmCheA HPT domain - NMR<BR />
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| [[2ch4]] - TmCheA kinase and regulatory domains + CheW
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| ===CheW===
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| [[1k0s]] – TmCheW<br />
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| [[2h09]] – EcCheW - NMR<BR />
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| ===Methyl-accepting chemotaxis protein===
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| [[1xbn]] – TtMche – ''Thermoanaerobacter tengcongensis''<BR />
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| [[3eee]], [[3iqb]], [[3lah]], [[3lai]], [[3sj5]] – TtMche H-Nox domain (mutant) <BR />
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| [[3tf0]], [[3tf1]] - TtMche H-Nox domain<BR />
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| [[3m0b]] - TtMche H-Nox domain Ru-porphyrin<BR />
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| [[3nvr]], [[3nvu]] – TtMche N terminal (mutant) <BR />
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| [[3g67]] – TmMche<BR />
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| [[3g6b]] – TmMche (mutant) <BR />
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| [[2ch7]] – TmMche cytoplasmic domain<BR />
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| [[1qu7]], [[2l9g]] – EcCheI cytoplasmic domain<BR />
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| [[2ld6]] – EcChe peptide - NMR<BR />
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| [[3atp]] - EcCheI ligand-binding domain + serine<BR />
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| [[1jmw]] - StChe ligand-binding domain (mutant) <BR />
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| [[2qhk]] – Che residues 31-203 – ''Vibrio parahaemolyticus''<BR />
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| [[3c8c]] – Che N-terminal – ''Vibrio cholerae''<BR />
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| [[3b47]] – Che periplasmic domain – ''Geobacter sulfurreducens''<BR />
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| ===Flagellar motor protein FLIN===
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| [[1yab]] – TmFLIN<BR />
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| ===Chemotaxis protein MotB===
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| [[3cyp]], [[3imp]] – HpMotB C terminal<br />
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| [[3cyq]] – HpMotB C terminal + N-acetylmuramic acid<BR />
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| [[2zov]], [[2zvy]], [[2zvz]] - StMotB C terminal<br />
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