Riboswitch: Difference between revisions
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The various classes of riboswitches discovered so far are differentiated by their respective '''ligands'''. Every class of riboswitch is characterized by an aptamer (binding site) domain, which provides the site for ligand binding, and an expression platform that undergoes conformational change. The sequences and structures of aptamer domains are highly conserved, and therefore exhibit little variation among riboswitches belonging to the same class. | The various classes of riboswitches discovered so far are differentiated by their respective '''ligands'''. Every class of riboswitch is characterized by an aptamer (binding site) domain, which provides the site for ligand binding, and an expression platform that undergoes conformational change. The sequences and structures of aptamer domains are highly conserved, and therefore exhibit little variation among riboswitches belonging to the same class. | ||
*'''M-box riboswitch''' | *'''M-box riboswitch''' recognizes Mg+2<ref>PMID:21315082</ref>. | ||
*'''YdaO riboswitch''' recognizes ATP<ref>PMID:23086297</ref>. | *'''YdaO riboswitch''' recognizes ATP<ref>PMID:23086297</ref>. | ||
*'''yybp-ykoy riboswitch''' recognizes Mn+2<ref>PMID:25794618</ref>. | *'''yybp-ykoy riboswitch''' recognizes Mn+2<ref>PMID:25794618</ref>. | ||
*'''PRPP riboswitch''' recognizes phosphoribosyl pyrophosphate<ref>PMID:29504937</ref>. | *'''PRPP riboswitch''' recognizes phosphoribosyl pyrophosphate<ref>PMID:29504937</ref>. | ||
*'''ZMP riboswitch''' recognizes aminoimidazole-4-carboxamide riboside 5'-monophosphate<ref>PMID:32795418</ref>. | |||
*'''ZTP riboswitch''' recognizes aminoimidazole-4-carboxamide riboside 5'-triphosphate<ref>PMID:32795418</ref>. | |||
*'''ThiM riboswitch''' recognizes thiamine pyrophosphate<ref>PMID:34644399</ref>. | |||
For details on guanine riboswitch see<br /> | For details on guanine riboswitch see<br /> | ||
* [[Guanine-Binding Riboswitch]]<br /> | * [[Guanine-Binding Riboswitch]]<br /> | ||