3vbz: Difference between revisions
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==Crystal structure of Taipoxin beta subunit isoform 2== | ==Crystal structure of Taipoxin beta subunit isoform 2== | ||
<StructureSection load='3vbz' size='340' side='right' caption='[[3vbz]], [[Resolution|resolution]] 1.76Å' scene=''> | <StructureSection load='3vbz' size='340' side='right'caption='[[3vbz]], [[Resolution|resolution]] 1.76Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3vbz]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3vbz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Oxyuranus_scutellatus_scutellatus Oxyuranus scutellatus scutellatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VBZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VBZ FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.76Å</td></tr> | ||
<tr | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vbz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vbz OCA], [https://pdbe.org/3vbz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vbz RCSB], [https://www.ebi.ac.uk/pdbsum/3vbz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vbz ProSAT]</span></td></tr> | ||
</table> | |||
<table> | == Function == | ||
[https://www.uniprot.org/uniprot/PA2HC_OXYSC PA2HC_OXYSC] Heterotrimer: Snake venom phospholipase A2 (PLA2) heterotrimer that acts as a potent presynaptic neurotoxin by blocking synaptic transmission and synaptic vesicle recycling. May act by binding in a calcium-dependent fashion to neurotonal pentraxin-1 (NPTX1) and neurotonal pentraxin-2 (NPTX2), but not to neuronal pentraxin receptor (NPTXR). Also binds to taipoxin-associated calcium binding protein 49 (RCN2), a protein localized in the lumen of endoplasmic reticulum. Monomer (beta chain): Snake venom phospholipase A2 homolog that is neither toxic nor enzymatically active. Does not bind calcium. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 3vbz" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[Phospholipase A2 homolog|Phospholipase A2 homolog]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Oxyuranus scutellatus scutellatus]] | [[Category: Oxyuranus scutellatus scutellatus]] | ||
[[Category: Beltramini | [[Category: Beltramini M]] | ||
[[Category: Cendron | [[Category: Cendron L]] | ||
[[Category: Micetic | [[Category: Micetic I]] | ||
[[Category: Paoli | [[Category: Paoli M]] | ||
[[Category: Polverino | [[Category: Polverino P]] | ||